Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)

A Verbrugghe; M Hesta; S Daminet; I Polis; Jens Juul Holst; J Buyse; B Wuyts; G P J Janssens

doi:10.1111/j.1439-0396.2011.01220.x

Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)

A Verbrugghe, M Hesta, S Daminet, I Polis, Jens Juul Holst, J Buyse, B Wuyts, G P J Janssens

19 Citations (Scopus)

Abstract

In six normal-weight and six obese cats, the metabolic effect of propionate absorbed from the colon was assessed. Two colonic infusions were tested in a crossover design with intervals of 4 weeks. The test solution contained 4 mmol sodium propionate per kg ideal body weight in a 0.2% NaCl solution. Normal saline was given as control solution. Solutions were infused into the hindgut over 30 min. Blood samples were obtained prior to and at various time points after starting the infusion. As body condition did not affect evaluated parameters, all data were pooled. Plasma glucose concentrations showed differences neither over time nor during or after infusion with propionate or control. Plasma amino acid concentrations rose over time (p

Original language	English
Journal	Journal of Animal Physiology and Animal Nutrition (Online)
Volume	96
Issue number	6
Pages (from-to)	1054-64
Number of pages	11
ISSN	1439-0396
DOIs	https://doi.org/10.1111/j.1439-0396.2011.01220.x
Publication status	Published - Dec 2012

Keywords

Absorption
Animal Feed
Animal Nutritional Physiological Phenomena
Animals
Cats
Colon
Cross-Over Studies
Diet
Female
Gluconeogenesis
Male
Obesity
Propionates

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1111/j.1439-0396.2011.01220.x

Cite this

@article{a40e980e475f4394812f929d9d28b1ac,

title = "Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)",

abstract = "In six normal-weight and six obese cats, the metabolic effect of propionate absorbed from the colon was assessed. Two colonic infusions were tested in a crossover design with intervals of 4 weeks. The test solution contained 4 mmol sodium propionate per kg ideal body weight in a 0.2% NaCl solution. Normal saline was given as control solution. Solutions were infused into the hindgut over 30 min. Blood samples were obtained prior to and at various time points after starting the infusion. As body condition did not affect evaluated parameters, all data were pooled. Plasma glucose concentrations showed differences neither over time nor during or after infusion with propionate or control. Plasma amino acid concentrations rose over time (p ",

keywords = "Absorption, Animal Feed, Animal Nutritional Physiological Phenomena, Animals, Cats, Colon, Cross-Over Studies, Diet, Female, Gluconeogenesis, Male, Obesity, Propionates",

author = "A Verbrugghe and M Hesta and S Daminet and I Polis and Holst, {Jens Juul} and J Buyse and B Wuyts and Janssens, {G P J}",

note = "{\textcopyright} 2011 Blackwell Verlag GmbH.",

year = "2012",

month = dec,

doi = "10.1111/j.1439-0396.2011.01220.x",

language = "English",

volume = "96",

pages = "1054--64",

journal = "Journal of Animal Physiology and Animal Nutrition (Online)",

issn = "1439-0396",

publisher = "Wiley-Blackwell",

number = "6",

}

TY - JOUR

T1 - Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)

AU - Verbrugghe, A

AU - Hesta, M

AU - Daminet, S

AU - Polis, I

AU - Holst, Jens Juul

AU - Buyse, J

AU - Wuyts, B

AU - Janssens, G P J

PY - 2012/12

Y1 - 2012/12

N2 - In six normal-weight and six obese cats, the metabolic effect of propionate absorbed from the colon was assessed. Two colonic infusions were tested in a crossover design with intervals of 4 weeks. The test solution contained 4 mmol sodium propionate per kg ideal body weight in a 0.2% NaCl solution. Normal saline was given as control solution. Solutions were infused into the hindgut over 30 min. Blood samples were obtained prior to and at various time points after starting the infusion. As body condition did not affect evaluated parameters, all data were pooled. Plasma glucose concentrations showed differences neither over time nor during or after infusion with propionate or control. Plasma amino acid concentrations rose over time (p

AB - In six normal-weight and six obese cats, the metabolic effect of propionate absorbed from the colon was assessed. Two colonic infusions were tested in a crossover design with intervals of 4 weeks. The test solution contained 4 mmol sodium propionate per kg ideal body weight in a 0.2% NaCl solution. Normal saline was given as control solution. Solutions were infused into the hindgut over 30 min. Blood samples were obtained prior to and at various time points after starting the infusion. As body condition did not affect evaluated parameters, all data were pooled. Plasma glucose concentrations showed differences neither over time nor during or after infusion with propionate or control. Plasma amino acid concentrations rose over time (p

KW - Absorption

KW - Animal Feed

KW - Animal Nutritional Physiological Phenomena

KW - Animals

KW - Cats

KW - Colon

KW - Cross-Over Studies

KW - Diet

KW - Female

KW - Gluconeogenesis

KW - Male

KW - Obesity

KW - Propionates

U2 - 10.1111/j.1439-0396.2011.01220.x

DO - 10.1111/j.1439-0396.2011.01220.x

M3 - Journal article

C2 - 21895780

SN - 1439-0396

VL - 96

SP - 1054

EP - 1064

JO - Journal of Animal Physiology and Animal Nutrition (Online)

JF - Journal of Animal Physiology and Animal Nutrition (Online)

IS - 6

ER -

Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this