Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study

Kazi Ishtiak-Ahmed; Åse Marie Hansen; Erik Lykke Mortensen; Anne Helene Garde; Ane Nørgaard; Finn Gyntelberg; Naja Hulvej Rod; Sabrina Islamoska; Rikke Lund; Thien Kieu Thi Phung; Eva Prescott; Gunhild Waldemar; Kirsten Nabe-Nielsen

doi:10.1007/s00420-018-1365-9

Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study

Kazi Ishtiak-Ahmed, Åse Marie Hansen, Erik Lykke Mortensen, Anne Helene Garde, Ane Nørgaard, Finn Gyntelberg, Naja Hulvej Rod, Sabrina Islamoska, Rikke Lund, Thien Kieu Thi Phung, Eva Prescott, Gunhild Waldemar, Kirsten Nabe-Nielsen

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Abstract

PURPOSE: Only a few studies have investigated the impact of negative aspects of social relations on cognitive function, and they have shown mixed results. Conflicts at work are part of the negative aspects of social relations, but the impact of experiencing conflicts at work has not yet been investigated as a risk factor for dementia. Therefore, we investigated whether experiencing prolonged or serious conflicts with a supervisor or colleagues at work was associated with incident dementia in old age.

METHODS: We analyzed data of 6,436 men and women from the third survey of the Copenhagen City Heart Study. At baseline in 1991-1994, the participants reported whether they had ever had a prolonged or serious conflict at work. The participants were followed until 2014. We used Poisson regression to estimate incidence rate ratios (IRR) and their 95% confidence intervals (CI).

RESULTS: After adjusting for potential confounders, the IRR for dementia was 1.53 (95% CI 0.77-3.03) among participants who had reported having prolonged or serious conflicts both with a supervisor and colleagues compared with participants who had never had such conflicts. In separate analyses stratified by sex, the IRRs were 2.14 (95% Cl 0.97-4.71) for men and 0.98 (95% Cl 0.29-3.32) for women.

CONCLUSIONS: Our findings did not support an overall association between experiencing prolonged or serious conflicts at work and incident dementia. However, because of the large differences in the point estimates for men and women, future research could aim at investigating potential sex differences regarding the association between conflicts at work and dementia.

Original language	English
Journal	International Archives of Occupational and Environmental Health
Volume	92
Pages (from-to)	165-173
Number of pages	9
ISSN	0340-0131
DOIs	https://doi.org/10.1007/s00420-018-1365-9
Publication status	Published - 3 Feb 2019

Keywords

Alzheimer’s
Cohort study
Midlife risk factors
Negative aspects of social relations
Psychosocial work factors
Social relations

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Ishtiak-Ahmed, K., Hansen, Å. M., Mortensen, E. L., Garde, A. H., Nørgaard, A., Gyntelberg, F., Rod, N. H., Islamoska, S., Lund, R., Phung, T. K. T., Prescott, E., Waldemar, G., & Nabe-Nielsen, K. (2019). Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study. International Archives of Occupational and Environmental Health, 92, 165-173. https://doi.org/10.1007/s00420-018-1365-9

Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study. / Ishtiak-Ahmed, Kazi; Hansen, Åse Marie ; Mortensen, Erik Lykke et al.
In: International Archives of Occupational and Environmental Health, Vol. 92, 03.02.2019, p. 165-173.

Research output: Contribution to journal › Journal article › Research › peer-review

Ishtiak-Ahmed, K, Hansen, ÅM , Mortensen, EL, Garde, AH, Nørgaard, A, Gyntelberg, F, Rod, NH, Islamoska, S, Lund, R, Phung, TKT, Prescott, E , Waldemar, G & Nabe-Nielsen, K 2019, 'Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study', International Archives of Occupational and Environmental Health, vol. 92, pp. 165-173. https://doi.org/10.1007/s00420-018-1365-9

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title = "Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study",

abstract = "PURPOSE: Only a few studies have investigated the impact of negative aspects of social relations on cognitive function, and they have shown mixed results. Conflicts at work are part of the negative aspects of social relations, but the impact of experiencing conflicts at work has not yet been investigated as a risk factor for dementia. Therefore, we investigated whether experiencing prolonged or serious conflicts with a supervisor or colleagues at work was associated with incident dementia in old age.METHODS: We analyzed data of 6,436 men and women from the third survey of the Copenhagen City Heart Study. At baseline in 1991-1994, the participants reported whether they had ever had a prolonged or serious conflict at work. The participants were followed until 2014. We used Poisson regression to estimate incidence rate ratios (IRR) and their 95% confidence intervals (CI).RESULTS: After adjusting for potential confounders, the IRR for dementia was 1.53 (95% CI 0.77-3.03) among participants who had reported having prolonged or serious conflicts both with a supervisor and colleagues compared with participants who had never had such conflicts. In separate analyses stratified by sex, the IRRs were 2.14 (95% Cl 0.97-4.71) for men and 0.98 (95% Cl 0.29-3.32) for women.CONCLUSIONS: Our findings did not support an overall association between experiencing prolonged or serious conflicts at work and incident dementia. However, because of the large differences in the point estimates for men and women, future research could aim at investigating potential sex differences regarding the association between conflicts at work and dementia.",

keywords = "Alzheimer{\textquoteright}s, Cohort study, Midlife risk factors, Negative aspects of social relations, Psychosocial work factors, Social relations",

author = "Kazi Ishtiak-Ahmed and Hansen, {{\AA}se Marie} and Mortensen, {Erik Lykke} and Garde, {Anne Helene} and Ane N{\o}rgaard and Finn Gyntelberg and Rod, {Naja Hulvej} and Sabrina Islamoska and Rikke Lund and Phung, {Thien Kieu Thi} and Eva Prescott and Gunhild Waldemar and Kirsten Nabe-Nielsen",

year = "2019",

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doi = "10.1007/s00420-018-1365-9",

language = "English",

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journal = "International Archives of Occupational and Environmental Health",

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T1 - Prolonged or serious conflicts at work and incident dementia

T2 - a 23-year follow-up of the Copenhagen City Heart Study

AU - Ishtiak-Ahmed, Kazi

AU - Hansen, Åse Marie

AU - Mortensen, Erik Lykke

AU - Garde, Anne Helene

AU - Nørgaard, Ane

AU - Gyntelberg, Finn

AU - Rod, Naja Hulvej

AU - Islamoska, Sabrina

AU - Lund, Rikke

AU - Phung, Thien Kieu Thi

AU - Prescott, Eva

AU - Waldemar, Gunhild

AU - Nabe-Nielsen, Kirsten

PY - 2019/2/3

Y1 - 2019/2/3

N2 - PURPOSE: Only a few studies have investigated the impact of negative aspects of social relations on cognitive function, and they have shown mixed results. Conflicts at work are part of the negative aspects of social relations, but the impact of experiencing conflicts at work has not yet been investigated as a risk factor for dementia. Therefore, we investigated whether experiencing prolonged or serious conflicts with a supervisor or colleagues at work was associated with incident dementia in old age.METHODS: We analyzed data of 6,436 men and women from the third survey of the Copenhagen City Heart Study. At baseline in 1991-1994, the participants reported whether they had ever had a prolonged or serious conflict at work. The participants were followed until 2014. We used Poisson regression to estimate incidence rate ratios (IRR) and their 95% confidence intervals (CI).RESULTS: After adjusting for potential confounders, the IRR for dementia was 1.53 (95% CI 0.77-3.03) among participants who had reported having prolonged or serious conflicts both with a supervisor and colleagues compared with participants who had never had such conflicts. In separate analyses stratified by sex, the IRRs were 2.14 (95% Cl 0.97-4.71) for men and 0.98 (95% Cl 0.29-3.32) for women.CONCLUSIONS: Our findings did not support an overall association between experiencing prolonged or serious conflicts at work and incident dementia. However, because of the large differences in the point estimates for men and women, future research could aim at investigating potential sex differences regarding the association between conflicts at work and dementia.

AB - PURPOSE: Only a few studies have investigated the impact of negative aspects of social relations on cognitive function, and they have shown mixed results. Conflicts at work are part of the negative aspects of social relations, but the impact of experiencing conflicts at work has not yet been investigated as a risk factor for dementia. Therefore, we investigated whether experiencing prolonged or serious conflicts with a supervisor or colleagues at work was associated with incident dementia in old age.METHODS: We analyzed data of 6,436 men and women from the third survey of the Copenhagen City Heart Study. At baseline in 1991-1994, the participants reported whether they had ever had a prolonged or serious conflict at work. The participants were followed until 2014. We used Poisson regression to estimate incidence rate ratios (IRR) and their 95% confidence intervals (CI).RESULTS: After adjusting for potential confounders, the IRR for dementia was 1.53 (95% CI 0.77-3.03) among participants who had reported having prolonged or serious conflicts both with a supervisor and colleagues compared with participants who had never had such conflicts. In separate analyses stratified by sex, the IRRs were 2.14 (95% Cl 0.97-4.71) for men and 0.98 (95% Cl 0.29-3.32) for women.CONCLUSIONS: Our findings did not support an overall association between experiencing prolonged or serious conflicts at work and incident dementia. However, because of the large differences in the point estimates for men and women, future research could aim at investigating potential sex differences regarding the association between conflicts at work and dementia.

KW - Alzheimer’s

KW - Cohort study

KW - Midlife risk factors

KW - Negative aspects of social relations

KW - Psychosocial work factors

KW - Social relations

U2 - 10.1007/s00420-018-1365-9

DO - 10.1007/s00420-018-1365-9

M3 - Journal article

C2 - 30370497

SN - 0340-0131

VL - 92

SP - 165

EP - 173

JO - International Archives of Occupational and Environmental Health

JF - International Archives of Occupational and Environmental Health

ER -

Prolonged or serious conflicts at work and incident dementia: a 23-year follow-up of the Copenhagen City Heart Study

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Keywords

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