Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II

Timothy M.E. Davis; Kerry Hunt; David G. Bruce; Sergio Starkstein; Timothy Skinner; Daniel McAullay; Wendy A. Davis

doi:10.1016/j.diabres.2014.12.014

Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II

Timothy M.E. Davis^*, Kerry Hunt, David G. Bruce, Sergio Starkstein, Timothy Skinner, Daniel McAullay, Wendy A. Davis

^*Corresponding author for this work

11 Citations (Scopus)

Abstract

Aims: To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. Methods: Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression. Results: The 107 Aboriginal participants were younger (mean. ±. SD 54.3. ±. 11.8 vs 67.2. ±. 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (. P≤. 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (. P=. 0.16), 15.4% vs 4.1% had major depression (. P=. 0.029), and 68.8% vs 29.7% had untreated depression (. P=. 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (. P≤. 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group. Conclusions: Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.

Original language	English
Journal	Diabetes Research and Clinical Practice
Volume	107
Issue number	3
Pages (from-to)	384-391
Number of pages	8
ISSN	0168-8227
DOIs	https://doi.org/10.1016/j.diabres.2014.12.014
Publication status	Published - 1 Jan 2015

Keywords

Aboriginal
Antidepressant treatment
Depression
Metabolic control
Type 2 diabetes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.diabres.2014.12.014

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Davis, T. M. E., Hunt, K., Bruce, D. G., Starkstein, S., Skinner, T., McAullay, D., & Davis, W. A. (2015). Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II. Diabetes Research and Clinical Practice, 107(3), 384-391. https://doi.org/10.1016/j.diabres.2014.12.014

Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes : The Fremantle Diabetes Study Phase II. / Davis, Timothy M.E.; Hunt, Kerry; Bruce, David G. et al.

In: Diabetes Research and Clinical Practice, Vol. 107, No. 3, 01.01.2015, p. 384-391.

Research output: Contribution to journal › Journal article › Research › peer-review

Davis, TME, Hunt, K, Bruce, DG, Starkstein, S, Skinner, T, McAullay, D & Davis, WA 2015, 'Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II', Diabetes Research and Clinical Practice, vol. 107, no. 3, pp. 384-391. https://doi.org/10.1016/j.diabres.2014.12.014

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abstract = "Aims: To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. Methods: Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression. Results: The 107 Aboriginal participants were younger (mean. ±. SD 54.3. ±. 11.8 vs 67.2. ±. 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (. P≤. 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (. P=. 0.16), 15.4% vs 4.1% had major depression (. P=. 0.029), and 68.8% vs 29.7% had untreated depression (. P=. 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (. P≤. 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group. Conclusions: Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.",

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AU - Bruce, David G.

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AU - Skinner, Timothy

AU - McAullay, Daniel

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N2 - Aims: To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. Methods: Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression. Results: The 107 Aboriginal participants were younger (mean. ±. SD 54.3. ±. 11.8 vs 67.2. ±. 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (. P≤. 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (. P=. 0.16), 15.4% vs 4.1% had major depression (. P=. 0.029), and 68.8% vs 29.7% had untreated depression (. P=. 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (. P≤. 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group. Conclusions: Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.

AB - Aims: To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. Methods: Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression. Results: The 107 Aboriginal participants were younger (mean. ±. SD 54.3. ±. 11.8 vs 67.2. ±. 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (. P≤. 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (. P=. 0.16), 15.4% vs 4.1% had major depression (. P=. 0.029), and 68.8% vs 29.7% had untreated depression (. P=. 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (. P≤. 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group. Conclusions: Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.

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KW - Antidepressant treatment

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KW - Metabolic control

KW - Type 2 diabetes

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Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II

Abstract

Keywords

UN SDGs

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