Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II

Timothy M.E. Davis; Kerry Hunt; David G. Bruce; Sergio Starkstein; Timothy Skinner; Daniel McAullay; Wendy A. Davis

doi:10.1016/j.diabres.2014.12.014

Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II

Timothy M.E. Davis^*, Kerry Hunt, David G. Bruce, Sergio Starkstein, Timothy Skinner, Daniel McAullay, Wendy A. Davis

^*Corresponding author af dette arbejde

11 Citationer (Scopus)

Abstract

Aims: To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. Methods: Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression. Results: The 107 Aboriginal participants were younger (mean. ±. SD 54.3. ±. 11.8 vs 67.2. ±. 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (. P≤. 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (. P=. 0.16), 15.4% vs 4.1% had major depression (. P=. 0.029), and 68.8% vs 29.7% had untreated depression (. P=. 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (. P≤. 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group. Conclusions: Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.

Originalsprog	Engelsk
Tidsskrift	Diabetes Research and Clinical Practice
Vol/bind	107
Udgave nummer	3
Sider (fra-til)	384-391
Antal sider	8
ISSN	0168-8227
DOI	https://doi.org/10.1016/j.diabres.2014.12.014
Status	Udgivet - 1 jan. 2015

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Davis, T. M. E., Hunt, K., Bruce, D. G., Starkstein, S., Skinner, T., McAullay, D., & Davis, W. A. (2015). Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II. Diabetes Research and Clinical Practice, 107(3), 384-391. https://doi.org/10.1016/j.diabres.2014.12.014

Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes : The Fremantle Diabetes Study Phase II. / Davis, Timothy M.E.; Hunt, Kerry; Bruce, David G. et al.

I: Diabetes Research and Clinical Practice, Bind 107, Nr. 3, 01.01.2015, s. 384-391.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Davis, TME, Hunt, K, Bruce, DG, Starkstein, S, Skinner, T, McAullay, D & Davis, WA 2015, 'Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II', Diabetes Research and Clinical Practice, bind 107, nr. 3, s. 384-391. https://doi.org/10.1016/j.diabres.2014.12.014

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title = "Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II",

abstract = "Aims: To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. Methods: Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression. Results: The 107 Aboriginal participants were younger (mean. ±. SD 54.3. ±. 11.8 vs 67.2. ±. 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (. P≤. 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (. P=. 0.16), 15.4% vs 4.1% had major depression (. P=. 0.029), and 68.8% vs 29.7% had untreated depression (. P=. 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (. P≤. 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group. Conclusions: Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.",

keywords = "Aboriginal, Antidepressant treatment, Depression, Metabolic control, Type 2 diabetes",

author = "Davis, {Timothy M.E.} and Kerry Hunt and Bruce, {David G.} and Sergio Starkstein and Timothy Skinner and Daniel McAullay and Davis, {Wendy A.}",

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T1 - Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes

T2 - The Fremantle Diabetes Study Phase II

AU - Davis, Timothy M.E.

AU - Hunt, Kerry

AU - Bruce, David G.

AU - Starkstein, Sergio

AU - Skinner, Timothy

AU - McAullay, Daniel

AU - Davis, Wendy A.

PY - 2015/1/1

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N2 - Aims: To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. Methods: Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression. Results: The 107 Aboriginal participants were younger (mean. ±. SD 54.3. ±. 11.8 vs 67.2. ±. 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (. P≤. 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (. P=. 0.16), 15.4% vs 4.1% had major depression (. P=. 0.029), and 68.8% vs 29.7% had untreated depression (. P=. 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (. P≤. 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group. Conclusions: Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.

AB - Aims: To determine the prevalence and associates of depression in Aboriginal and Anglo-Celt (AC) Australians with type 2 diabetes. Methods: Community-based patients were screened using the Patient Health Questionnaire (PHQ-9) as part of detailed assessment. The prevalence of any current depression, major depression and antidepressant use by racial group was compared after adjustment for age, sex, educational attainment and marital status. Multiple logistic regression was used to determine associates of current depression. Results: The 107 Aboriginal participants were younger (mean. ±. SD 54.3. ±. 11.8 vs 67.2. ±. 10.6 years), less often male (34.6% vs 50.9%) and married (39.3% vs 61.7%), and more likely to smoke (44.6% vs 8.1%) than the 793 AC subjects (. P≤. 0.002). Fifty-two Aboriginal (48.5%) and 772 AC participants (97.4%) completed the PHQ-9; these Aboriginals had similar socio-demographic, anthropometric and diabetes-related characteristics to those without PHQ-9 data. A quarter of the Aboriginals had current depression vs 10.6% of ACs (. P=. 0.16), 15.4% vs 4.1% had major depression (. P=. 0.029), and 68.8% vs 29.7% had untreated depression (. P=. 0.032). Compared with non-depressed participants, patients with current depression were younger and more likely to smoke, to be overweight/obese and to have worse glycaemic control (. P≤. 0.024). Significant independent associates of current depression were educational attainment (inversely), smoking status, body mass index and fasting plasma glucose in the AC group and alcohol use in the Aboriginal group. Conclusions: Although prevalence of depression was not significantly increased in the Aboriginal patients, it was more likely to be major and untreated. Depression complicating type 2 diabetes is associated with adverse cardiovascular risk.

KW - Aboriginal

KW - Antidepressant treatment

KW - Depression

KW - Metabolic control

KW - Type 2 diabetes

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AN - SCOPUS:84924205606

SN - 0168-8227

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Prevalence of depression and its associations with cardio-metabolic control in Aboriginal and Anglo-Celt patients with type 2 diabetes: The Fremantle Diabetes Study Phase II

Abstract

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