Pineal function: impact of microarray analysis

David C Klein; Michael J Bailey; David A Carter; Jong-so Kim; Qiong Shi; Anthony K Ho; Constance L Chik; Pascaline Gaildrat; Fabrice Morin; Surajit Ganguly; Martin F Rath; Morten Møller; David Sugden; Zoila G Rangel; Peter J Munson; Joan L Weller; Steven L Coon

doi:10.1016/j.mce.2009.07.010

Pineal function: impact of microarray analysis

David C Klein, Michael J Bailey, David A Carter, Jong-so Kim, Qiong Shi, Anthony K Ho, Constance L Chik, Pascaline Gaildrat, Fabrice Morin, Surajit Ganguly, Martin F Rath, Morten Møller, David Sugden, Zoila G Rangel, Peter J Munson, Joan L Weller, Steven L Coon

40 Citations (Scopus)

Abstract

Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.

Original language	English
Journal	Molecular and Cellular Endocrinology
Volume	314
Issue number	2
Pages (from-to)	170-83
Number of pages	13
ISSN	0303-7207
DOIs	https://doi.org/10.1016/j.mce.2009.07.010
Publication status	Published - 2009

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Klein, D. C., Bailey, M. J., Carter, D. A., Kim, J., Shi, Q., Ho, A. K., Chik, C. L., Gaildrat, P., Morin, F., Ganguly, S., Rath, M. F., Møller, M., Sugden, D., Rangel, Z. G., Munson, P. J., Weller, J. L., & Coon, S. L. (2009). Pineal function: impact of microarray analysis. Molecular and Cellular Endocrinology, 314(2), 170-83. https://doi.org/10.1016/j.mce.2009.07.010

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title = "Pineal function: impact of microarray analysis",

abstract = "Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.",

author = "Klein, {David C} and Bailey, {Michael J} and Carter, {David A} and Jong-so Kim and Qiong Shi and Ho, {Anthony K} and Chik, {Constance L} and Pascaline Gaildrat and Fabrice Morin and Surajit Ganguly and Rath, {Martin F} and Morten M{\o}ller and David Sugden and Rangel, {Zoila G} and Munson, {Peter J} and Weller, {Joan L} and Coon, {Steven L}",

note = "Keywords: Animals; Circadian Rhythm; Humans; Melatonin; Neurons; Oligonucleotide Array Sequence Analysis; Pineal Gland; Signal Transduction",

year = "2009",

doi = "10.1016/j.mce.2009.07.010",

language = "English",

volume = "314",

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T1 - Pineal function: impact of microarray analysis

AU - Klein, David C

AU - Bailey, Michael J

AU - Carter, David A

AU - Kim, Jong-so

AU - Shi, Qiong

AU - Ho, Anthony K

AU - Chik, Constance L

AU - Gaildrat, Pascaline

AU - Morin, Fabrice

AU - Ganguly, Surajit

AU - Rath, Martin F

AU - Møller, Morten

AU - Sugden, David

AU - Rangel, Zoila G

AU - Munson, Peter J

AU - Weller, Joan L

AU - Coon, Steven L

N1 - Keywords: Animals; Circadian Rhythm; Humans; Melatonin; Neurons; Oligonucleotide Array Sequence Analysis; Pineal Gland; Signal Transduction

PY - 2009

Y1 - 2009

N2 - Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.

AB - Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function.

U2 - 10.1016/j.mce.2009.07.010

DO - 10.1016/j.mce.2009.07.010

M3 - Journal article

C2 - 19622385

SN - 0303-7207

VL - 314

SP - 170

EP - 183

JO - Molecular and Cellular Endocrinology

JF - Molecular and Cellular Endocrinology

IS - 2

ER -

Pineal function: impact of microarray analysis

Abstract

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