Optoepigenetics: An acetylation photoswitch

Andreas S Madsen, Christian A Olsen

    2 Citations (Scopus)

    Abstract

    Histone 3 lysine 9 acetylation (H3K9ac) levels were modulated by photoresponsive histone deacetylase (HDAC) inhibitors to perturb the transcription of genes involved in cell cycle regulation and mitochondrial function.
    Original languageEnglish
    JournalNature Chemical Biology
    Volume12
    Issue number5
    Pages (from-to)306-7
    Number of pages2
    ISSN1552-4450
    DOIs
    Publication statusPublished - 1 May 2016

    Keywords

    • Acetylation
    • Azo Compounds
    • Light
    • Comment
    • News

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