Optoepigenetics: An acetylation photoswitch

Andreas S Madsen; Christian A Olsen

doi:10.1038/nchembio.2049

Optoepigenetics: An acetylation photoswitch

2 Citationer (Scopus)

Abstract

Histone 3 lysine 9 acetylation (H3K9ac) levels were modulated by photoresponsive histone deacetylase (HDAC) inhibitors to perturb the transcription of genes involved in cell cycle regulation and mitochondrial function.

Originalsprog	Engelsk
Tidsskrift	Nature Chemical Biology
Vol/bind	12
Udgave nummer	5
Sider (fra-til)	306-7
Antal sider	2
ISSN	1552-4450
DOI	https://doi.org/10.1038/nchembio.2049
Status	Udgivet - 1 maj 2016

Adgang til dokumentet

10.1038/nchembio.2049

Citationsformater

@article{43eb8e7fcafd4b1bb960b68963673e04,

title = "Optoepigenetics: An acetylation photoswitch",

abstract = "Histone 3 lysine 9 acetylation (H3K9ac) levels were modulated by photoresponsive histone deacetylase (HDAC) inhibitors to perturb the transcription of genes involved in cell cycle regulation and mitochondrial function.",

keywords = "Acetylation, Azo Compounds, Light, Comment, News",

author = "Madsen, {Andreas S} and Olsen, {Christian A}",

year = "2016",

month = may,

day = "1",

doi = "10.1038/nchembio.2049",

language = "English",

volume = "12",

pages = "306--7",

journal = "Nature Chemical Biology",

issn = "1552-4450",

publisher = "nature publishing group",

number = "5",

}

TY - JOUR

T1 - Optoepigenetics

T2 - An acetylation photoswitch

AU - Madsen, Andreas S

AU - Olsen, Christian A

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Histone 3 lysine 9 acetylation (H3K9ac) levels were modulated by photoresponsive histone deacetylase (HDAC) inhibitors to perturb the transcription of genes involved in cell cycle regulation and mitochondrial function.

AB - Histone 3 lysine 9 acetylation (H3K9ac) levels were modulated by photoresponsive histone deacetylase (HDAC) inhibitors to perturb the transcription of genes involved in cell cycle regulation and mitochondrial function.

KW - Acetylation

KW - Azo Compounds

KW - Light

KW - Comment

KW - News

U2 - 10.1038/nchembio.2049

DO - 10.1038/nchembio.2049

M3 - Journal article

C2 - 26974815

SN - 1552-4450

VL - 12

SP - 306

EP - 307

JO - Nature Chemical Biology

JF - Nature Chemical Biology

IS - 5

ER -