NNMT: A Bad Actor in Fat Makes Good in Liver

Samuel A.J. Trammell; Charles Brenner

doi:10.1016/j.cmet.2015.07.017

NNMT: A Bad Actor in Fat Makes Good in Liver

Samuel A.J. Trammell, Charles Brenner^*

^*Corresponding author for this work

26 Citations (Scopus)

Abstract

High adipose expression of NNMT, an enzyme that converts nicotinamide to 1-methyl-nicotinamide, correlates with adiposity. Though murine NNMT knockdown in fat and liver prevents weight gain on high-fat diet, Hong et al. (2015) now show that high hepatic expression of NNMT improves lipid parameters via SIRT1 stabilization.

Original language	English
Journal	Cell Metabolism
Volume	22
Issue number	2
Pages (from-to)	200-201
Number of pages	2
ISSN	1550-4131
DOIs	https://doi.org/10.1016/j.cmet.2015.07.017
Publication status	Published - 4 Aug 2015

Access to Document

10.1016/j.cmet.2015.07.017

Cite this

@article{f46da04489b044818500f39c8ff61100,

title = "NNMT: A Bad Actor in Fat Makes Good in Liver",

abstract = "High adipose expression of NNMT, an enzyme that converts nicotinamide to 1-methyl-nicotinamide, correlates with adiposity. Though murine NNMT knockdown in fat and liver prevents weight gain on high-fat diet, Hong et al. (2015) now show that high hepatic expression of NNMT improves lipid parameters via SIRT1 stabilization.",

author = "Trammell, {Samuel A.J.} and Charles Brenner",

year = "2015",

month = aug,

day = "4",

doi = "10.1016/j.cmet.2015.07.017",

language = "English",

volume = "22",

pages = "200--201",

journal = "Cell Metabolism",

issn = "1550-4131",

publisher = "Cell Press",

number = "2",

}

TY - JOUR

T1 - NNMT

T2 - A Bad Actor in Fat Makes Good in Liver

AU - Trammell, Samuel A.J.

AU - Brenner, Charles

PY - 2015/8/4

Y1 - 2015/8/4

N2 - High adipose expression of NNMT, an enzyme that converts nicotinamide to 1-methyl-nicotinamide, correlates with adiposity. Though murine NNMT knockdown in fat and liver prevents weight gain on high-fat diet, Hong et al. (2015) now show that high hepatic expression of NNMT improves lipid parameters via SIRT1 stabilization.

AB - High adipose expression of NNMT, an enzyme that converts nicotinamide to 1-methyl-nicotinamide, correlates with adiposity. Though murine NNMT knockdown in fat and liver prevents weight gain on high-fat diet, Hong et al. (2015) now show that high hepatic expression of NNMT improves lipid parameters via SIRT1 stabilization.

UR - http://www.scopus.com/inward/record.url?scp=84938593243&partnerID=8YFLogxK

U2 - 10.1016/j.cmet.2015.07.017

DO - 10.1016/j.cmet.2015.07.017

M3 - Editorial

C2 - 26244929

AN - SCOPUS:84938593243

SN - 1550-4131

VL - 22

SP - 200

EP - 201

JO - Cell Metabolism

JF - Cell Metabolism

IS - 2

ER -

NNMT: A Bad Actor in Fat Makes Good in Liver

Abstract

Access to Document

Other files and links

Fingerprint

Cite this