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Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1
Jenq-Lin Yang, Takashi Tadokoro,
Guido Keijzers
, Mark P Mattson,
Vilhelm Bohr
Molecular Aging Program
Individualized Health
73
Citations (Scopus)
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Dive into the research topics of 'Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1'. Together they form a unique fingerprint.
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Medicine & Life Sciences
DNA-(Apurinic or Apyrimidinic Site) Lyase
100%
Cyclic AMP Response Element-Binding Protein
84%
Glutamic Acid
58%
DNA Damage
58%
Up-Regulation
48%
Neurons
41%
Glutamate Receptors
31%
5,10,15,20-tetra(4-pyridyl)porphyrin
23%
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin
17%
DNA Repair
17%
KN 93
15%
Aptitude
13%
Calcium-Calmodulin-Dependent Protein Kinases
12%
Proteins
10%
Chlorides
10%
Protein Binding
9%
RNA Interference
9%
Superoxide Dismutase
8%
Neurotransmitter Agents
8%
Permeability
8%
Reactive Oxygen Species
7%
Learning
7%
Memory
6%
Phosphorylation
6%
Membranes
5%
Messenger RNA
5%
Brain
4%
Genes
3%
Chemical Compounds
KN-93
20%
Protein
19%
Phosphotransferase Inhibitor
12%
Depolarization
10%
Neurotransmitter
10%
Non Toxic
9%
Superoxide
9%
Permeability
7%
Pore
6%
Chloride
5%
Dioxygen
4%