Natural products from microbes associated with insects

Christine Beemelmanns; Huijuan Guo; Maja Rischer; Michael Thomas-Poulsen

doi:10.3762/bjoc.12.34

Natural products from microbes associated with insects

Christine Beemelmanns, Huijuan Guo, Maja Rischer, Michael Thomas-Poulsen

Ecology and Evolution

54 Citations (Scopus)

109 Downloads (Pure)

Abstract

Here we review discoveries of secondary metabolites from microbes associated with insects. We mainly focus on natural products, where the ecological role has been at least partially elucidated, and/or the pharmaceutical properties evaluated, and on compounds with unique structural features. We demonstrate that the exploration of specific microbial-host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed light on the ecology and evolution of defensive associations.

Original language	English
Journal	Beilstein Journal of Organic Chemistry
Volume	12
Pages (from-to)	314-327
Number of pages	14
ISSN	2195-951X
DOIs	https://doi.org/10.3762/bjoc.12.34
Publication status	Published - 19 Feb 2016

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10.3762/bjoc.12.34Licence: CC BY

Natural products from microbes associated with insectsFinal published version, 1.39 MBLicence: CC BY

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AU - Guo, Huijuan

AU - Rischer, Maja

AU - Thomas-Poulsen, Michael

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Y1 - 2016/2/19

N2 - Here we review discoveries of secondary metabolites from microbes associated with insects. We mainly focus on natural products, where the ecological role has been at least partially elucidated, and/or the pharmaceutical properties evaluated, and on compounds with unique structural features. We demonstrate that the exploration of specific microbial-host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed light on the ecology and evolution of defensive associations.

AB - Here we review discoveries of secondary metabolites from microbes associated with insects. We mainly focus on natural products, where the ecological role has been at least partially elucidated, and/or the pharmaceutical properties evaluated, and on compounds with unique structural features. We demonstrate that the exploration of specific microbial-host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed light on the ecology and evolution of defensive associations.

U2 - 10.3762/bjoc.12.34

DO - 10.3762/bjoc.12.34

M3 - Journal article

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SN - 2195-951X

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EP - 327

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

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Natural products from microbes associated with insects

Abstract

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