Abstract
NAC proteins are transcription factors, which have so far been found only in land plants. They play important roles in development, abiotic and biotic stress responses, and biosynthesis. Their DNA-binding domain, the NAC domain, interacts with the CGT[AG] core sequence in target genes, and its structure and DNA-binding mode suggest an evolutionary relationship with WRKY and glial cells missing (GCM) transcription factors. The specific molecular interactions of NAC proteins with specific genes and other proteins are essential for regulation of networks with NAC proteins and genes as central components. The network of Arabidopsis ANAC019, ANAC055, and ANAC072 regulates both abiotic stress responses and pathogen sensitivity, and in addition the corresponding emerging network for rice reveals the epigenetic regulation of growth. Knowledge of NAC protein structure-function relationships and networks is essential for the future application of NAC proteins in agriculture.
| Original language | English |
|---|---|
| Title of host publication | Plant transcription factors : evolutionary, structural and functional aspects |
| Editors | Daniel H. Gonzalez |
| Number of pages | 14 |
| Publisher | Academic Press |
| Publication date | 2016 |
| Pages | 199-212 |
| Chapter | 13 |
| ISBN (Print) | 9780128008546 |
| ISBN (Electronic) | 9780128011270 |
| DOIs | |
| Publication status | Published - 2016 |