NAC transcription factors: from structure to function in stress-associated networks

TY - CHAP

T1 - NAC transcription factors

T2 - from structure to function in stress-associated networks

AU - Welner, Ditte H.

AU - Deeba, Farah

AU - Lo Leggio, Leila

AU - Skriver, Karen

PY - 2016

Y1 - 2016

N2 - NAC proteins are transcription factors, which have so far been found only in land plants. They play important roles in development, abiotic and biotic stress responses, and biosynthesis. Their DNA-binding domain, the NAC domain, interacts with the CGT[AG] core sequence in target genes, and its structure and DNA-binding mode suggest an evolutionary relationship with WRKY and glial cells missing (GCM) transcription factors. The specific molecular interactions of NAC proteins with specific genes and other proteins are essential for regulation of networks with NAC proteins and genes as central components. The network of Arabidopsis ANAC019, ANAC055, and ANAC072 regulates both abiotic stress responses and pathogen sensitivity, and in addition the corresponding emerging network for rice reveals the epigenetic regulation of growth. Knowledge of NAC protein structure-function relationships and networks is essential for the future application of NAC proteins in agriculture.

AB - NAC proteins are transcription factors, which have so far been found only in land plants. They play important roles in development, abiotic and biotic stress responses, and biosynthesis. Their DNA-binding domain, the NAC domain, interacts with the CGT[AG] core sequence in target genes, and its structure and DNA-binding mode suggest an evolutionary relationship with WRKY and glial cells missing (GCM) transcription factors. The specific molecular interactions of NAC proteins with specific genes and other proteins are essential for regulation of networks with NAC proteins and genes as central components. The network of Arabidopsis ANAC019, ANAC055, and ANAC072 regulates both abiotic stress responses and pathogen sensitivity, and in addition the corresponding emerging network for rice reveals the epigenetic regulation of growth. Knowledge of NAC protein structure-function relationships and networks is essential for the future application of NAC proteins in agriculture.

U2 - 10.1016/B978-0-12-800854-6.00013-0

DO - 10.1016/B978-0-12-800854-6.00013-0

M3 - Book chapter

SN - 9780128008546

SP - 199

EP - 212

BT - Plant transcription factors

A2 - Gonzalez , Daniel H.

PB - Academic Press

ER -