Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of alpha-synuclein aggregation

Patrick Flagmeier, Georg Meisl, Michele Vendruscolo, Tuomas P. J. Knowles, Christopher M. Dobson, Alexander K. Buell, Celine Galvagnion

108 Citations (Scopus)
Original languageEnglish
JournalProceedings of the National Academy of Sciences of the United States of America
Volume113
Issue number37
Pages (from-to)10328-10333
ISSN0027-8424
DOIs
Publication statusPublished - 13 Sept 2016
Externally publishedYes

Keywords

  • lipid-induced aggregation
  • seeded aggregation
  • kinetic analysis
  • familial Parkinson's disease
  • neurodegenerative disease

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