Monocyte functions in diabetes mellitus

C Geisler; T Almdal; J Bennedsen; J M Rhodes; K Kølendorf

Monocyte functions in diabetes mellitus

C Geisler, T Almdal, J Bennedsen, J M Rhodes, K Kølendorf

Department of Immunology and Microbiology

31 Citations (Scopus)

Abstract

The aim of this study was to investigate the functions of monocytes obtained from 14 patients with diabetes mellitus (DM) compared with those of monocytes from healthy individuals. It was found that the total number of circulating monocytes in the 14 diabetic patients was lower than that from the healthy individuals. Phagocytosis of Candida albicans was decreased in the monocytes from the patients, whereas pinocytosis of acridine and phagocytosis of latex and sheep red blood cells were normal. The chemotactic response towards casein was enhanced. The possible consequences of these findings for the elucidation of concomitant infections in diabetic patients are discussed.

Original language	English
Book series	APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum
Volume	90
Issue number	1
Pages (from-to)	33-7
Number of pages	4
ISSN	0903-465X
Publication status	Published - 1982

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title = "Monocyte functions in diabetes mellitus",

abstract = "The aim of this study was to investigate the functions of monocytes obtained from 14 patients with diabetes mellitus (DM) compared with those of monocytes from healthy individuals. It was found that the total number of circulating monocytes in the 14 diabetic patients was lower than that from the healthy individuals. Phagocytosis of Candida albicans was decreased in the monocytes from the patients, whereas pinocytosis of acridine and phagocytosis of latex and sheep red blood cells were normal. The chemotactic response towards casein was enhanced. The possible consequences of these findings for the elucidation of concomitant infections in diabetic patients are discussed.",

author = "C Geisler and T Almdal and J Bennedsen and Rhodes, {J M} and K K{\o}lendorf",

note = "Keywords: Adult; Aged; Candida albicans; Chemotaxis, Leukocyte; Diabetes Mellitus; Female; Humans; Immunity, Cellular; Leukocyte Count; Male; Middle Aged; Monocytes; Phagocytosis; Pinocytosis",

year = "1982",

language = "English",

volume = "90",

pages = "33--7",

journal = "APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum",

issn = "0903-465X",

publisher = "Wiley-Blackwell",

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TY - JOUR

T1 - Monocyte functions in diabetes mellitus

AU - Geisler, C

AU - Almdal, T

AU - Bennedsen, J

AU - Rhodes, J M

AU - Kølendorf, K

N1 - Keywords: Adult; Aged; Candida albicans; Chemotaxis, Leukocyte; Diabetes Mellitus; Female; Humans; Immunity, Cellular; Leukocyte Count; Male; Middle Aged; Monocytes; Phagocytosis; Pinocytosis

PY - 1982

Y1 - 1982

N2 - The aim of this study was to investigate the functions of monocytes obtained from 14 patients with diabetes mellitus (DM) compared with those of monocytes from healthy individuals. It was found that the total number of circulating monocytes in the 14 diabetic patients was lower than that from the healthy individuals. Phagocytosis of Candida albicans was decreased in the monocytes from the patients, whereas pinocytosis of acridine and phagocytosis of latex and sheep red blood cells were normal. The chemotactic response towards casein was enhanced. The possible consequences of these findings for the elucidation of concomitant infections in diabetic patients are discussed.

AB - The aim of this study was to investigate the functions of monocytes obtained from 14 patients with diabetes mellitus (DM) compared with those of monocytes from healthy individuals. It was found that the total number of circulating monocytes in the 14 diabetic patients was lower than that from the healthy individuals. Phagocytosis of Candida albicans was decreased in the monocytes from the patients, whereas pinocytosis of acridine and phagocytosis of latex and sheep red blood cells were normal. The chemotactic response towards casein was enhanced. The possible consequences of these findings for the elucidation of concomitant infections in diabetic patients are discussed.

M3 - Journal article

C2 - 7044041

SN - 0903-465X

VL - 90

SP - 33

EP - 37

JO - APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum

JF - APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum

IS - 1

ER -

Monocyte functions in diabetes mellitus

Abstract

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