Modeling Ca2+ Microdomains

Jens Christian Brasen; Jens Christian Brings Jacobsen; Niels-Henrik von Holstein-Rathlou

Modeling Ca2+ Microdomains

Jens Christian Brasen, Jens Christian Brings Jacobsen, Niels-Henrik von Holstein-Rathlou

Renal and Vascular Research

Abstract

The intracellular ionic concentrations are often regarded as being uniform across the cytosol. In recent years it has become evident, however, that there are local spaces within the cell where the concentration of free Ca²⁺can temporarily exceed the bulk concentration in the cytosol by orders of magnitudes and that these localized regions of high Ca²⁺concentration play important functional roles.

Original language	English
Title of host publication	Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development
Editors	Erik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan
Number of pages	18
Place of Publication	Wien
Publisher	Springer
Publication date	1 Jan 2012
Pages	201-218
Chapter	9
ISBN (Print)	978-3-7091-0417-0
Publication status	Published - 1 Jan 2012

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http://www.springer.com/biomed/pharmaceutical+science/book/978-3-7091-0417-0

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Brasen, J. C., Jacobsen, J. C. B., & von Holstein-Rathlou, N.-H. (2012). Modeling Ca2+ Microdomains. In E. Mosekilde, O. Sosnovtseva, & A. Rostami-Hodjegan (Eds.), Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development (pp. 201-218). Springer. http://www.springer.com/biomed/pharmaceutical+science/book/978-3-7091-0417-0

Modeling Ca2+ Microdomains. / Brasen, Jens Christian; Jacobsen, Jens Christian Brings ; von Holstein-Rathlou, Niels-Henrik.
Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development. ed. / Erik Mosekilde; Olga Sosnovtseva; Amin Rostami-Hodjegan. Wien: Springer, 2012. p. 201-218.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

Brasen, JC, Jacobsen, JCB & von Holstein-Rathlou, N-H 2012, Modeling Ca2+ Microdomains. in E Mosekilde, O Sosnovtseva & A Rostami-Hodjegan (eds), Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development. Springer, Wien, pp. 201-218. <http://www.springer.com/biomed/pharmaceutical+science/book/978-3-7091-0417-0>

Brasen, Jens Christian ; Jacobsen, Jens Christian Brings ; von Holstein-Rathlou, Niels-Henrik. / Modeling Ca2+ Microdomains. Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development. editor / Erik Mosekilde ; Olga Sosnovtseva ; Amin Rostami-Hodjegan. Wien : Springer, 2012. pp. 201-218

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Modeling Ca2+ Microdomains

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