Abstract

The intracellular ionic concentrations are often regarded as being uniform across the cytosol. In recent years it has become evident, however, that there are local spaces within the cell where the concentration of free Ca2+can temporarily exceed the bulk concentration in the cytosol by orders of magnitudes and that these localized regions of high Ca2+concentration play important functional roles.

OriginalsprogEngelsk
Titel Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development
RedaktørerErik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan
Antal sider18
UdgivelsesstedWien
ForlagSpringer
Publikationsdato1 jan. 2012
Sider201-218
Kapitel9
ISBN (Trykt)978-3-7091-0417-0
StatusUdgivet - 1 jan. 2012

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