Modeling Ca2+ Microdomains

TY - CHAP

T1 - Modeling Ca2+ Microdomains

AU - Brasen, Jens Christian

AU - Jacobsen, Jens Christian Brings

AU - von Holstein-Rathlou, Niels-Henrik

PY - 2012/1/1

Y1 - 2012/1/1

N2 - The intracellular ionic concentrations are often regarded as being uniform across the cytosol. In recent years it has become evident, however, that there are local spaces within the cell where the concentration of free Ca2+can temporarily exceed the bulk concentration in the cytosol by orders of magnitudes and that these localized regions of high Ca2+concentration play important functional roles.

AB - The intracellular ionic concentrations are often regarded as being uniform across the cytosol. In recent years it has become evident, however, that there are local spaces within the cell where the concentration of free Ca2+can temporarily exceed the bulk concentration in the cytosol by orders of magnitudes and that these localized regions of high Ca2+concentration play important functional roles.

M3 - Book chapter

SN - 978-3-7091-0417-0

SP - 201

EP - 218

BT - Biosimulation in Biomedical Research, Health Care and Drug Development Biosimulation in Biomedical Research, Health Care and Drug Development

A2 - Mosekilde, Erik

A2 - Sosnovtseva, Olga

A2 - Rostami-Hodjegan, Amin

PB - Springer

CY - Wien

ER -