@inbook{5af778cef1294b5f95f8151e4f1f18fe,
title = "Microwave-assisted solid-phase peptide synthesis using the biotage syro Wave{\texttrademark}",
abstract = "Fast and precise heating by microwave irradiation during solid-phase peptide synthesis (SPPS) can reduce reaction times as well as provide better purities and greater yields for the synthesis of difficult peptides. Microwave- assisted SPPS has proven to be a useful and reliable tool for the synthesis of peptides as well as small proteins. It is particularly well suited for sequences with a high propensity to form β-sheet-type structures and for sterically difficult couplings. In this protocol, conditions and detailed procedures are described for performing microwave-assisted SPPS using the Syro Wave{\texttrademark}. Here we describe the synthesis of two difficult peptide sequences: the first is derived from the C-terminus of the MuLV CTL epitope, the second is a de novo designed peptide with a C-terminal alkyne.",
keywords = "Backbone amide linker, Handle, Peptide, Aldehyde, Thioester, N-Alkyl amide, Cyclic peptide, Reductive amination",
author = "Leila Malik and Jensen, {Knud J{\o}rgen}",
year = "2013",
doi = "10.1007/978-1-62703-544-6_16",
language = "English",
isbn = "978-1-62703-543-9",
series = "Methods in Molecular Biology",
publisher = "Humana Press",
pages = "225--234",
editor = "Jensen, {Knud J.} and Shelton, {Pernille T.} and Pedersen, {S{\o}ren L.}",
booktitle = "Peptide synthesis and applications",
address = "United States",
}