TY - JOUR
T1 - Methylenedioxy- and methoxyflavones from Melicope coodeana syn. Euodia simplex
AU - Simonsen, Henrik Toft
AU - Larsen, Michael D
AU - Nielsen, Merete W
AU - Adsersen, Anne
AU - Olsen, Carl Erik
AU - Strasberg, Dominique
AU - Smitt, Ulla W
AU - Jaroszewski, Jerzy W
PY - 2002/8
Y1 - 2002/8
N2 - Three new natural products, 3,8-dimethoxy-5,7-dihydroxy-3',4'-methylenedioxyflavone, 3,6,8-trimethoxy-5,7-dihydroxy-3',4'-methylenedioxyflavone and 3,6,8,3',4'-pentamethoxy-5,7-dihydroxyflavone were isolated from Melicope coodeana syn. Euodia simplex (Rutaceae) along with 3,6,3'-trimethoxy-5,7,4'-trihydroxyflavone and 3,3'-dimethoxy-5,7,4'-trihydroxyflavone. The structural assignments are based on (1)H and (13)C NMR data, including discussion of the chemical shifts of C-2 in 3,5-dihydroxy- and 3-methoxy-5-hydroxyflavones. The presence of highly methoxylated and methylenedioxyflavones is characteristic of the genus Melicope, and the present findings support the recent transfer of Euodia simplex to Melicope.
AB - Three new natural products, 3,8-dimethoxy-5,7-dihydroxy-3',4'-methylenedioxyflavone, 3,6,8-trimethoxy-5,7-dihydroxy-3',4'-methylenedioxyflavone and 3,6,8,3',4'-pentamethoxy-5,7-dihydroxyflavone were isolated from Melicope coodeana syn. Euodia simplex (Rutaceae) along with 3,6,3'-trimethoxy-5,7,4'-trihydroxyflavone and 3,3'-dimethoxy-5,7,4'-trihydroxyflavone. The structural assignments are based on (1)H and (13)C NMR data, including discussion of the chemical shifts of C-2 in 3,5-dihydroxy- and 3-methoxy-5-hydroxyflavones. The presence of highly methoxylated and methylenedioxyflavones is characteristic of the genus Melicope, and the present findings support the recent transfer of Euodia simplex to Melicope.
KW - Flavonoids
KW - Molecular Structure
KW - Rutaceae
KW - Spectrum Analysis
U2 - 10.1016/S0031-9422(02)00083-3
DO - 10.1016/S0031-9422(02)00083-3
M3 - Journal article
C2 - 12150806
SN - 0031-9422
VL - 60
SP - 817
EP - 820
JO - Phytochemistry
JF - Phytochemistry
IS - 8
ER -