Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

Michele Mariotti; Fabian Leinisch; Diana Julie Leeming; Birte Svensson; Michael J. Davies; Per Hagglund

doi:10.1021/acs.jproteome.7b00881

Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

Michele Mariotti, Fabian Leinisch, Diana Julie Leeming, Birte Svensson, Michael J. Davies, Per Hagglund

Inflammation, Metabolism and Oxidation

16 Citations (Scopus)

Original language	English
Journal	Journal of Proteome Research
Volume	17
Issue number	6
Pages (from-to)	2017-2027
ISSN	1535-3893
DOIs	https://doi.org/10.1021/acs.jproteome.7b00881
Publication status	Published - 1 Jun 2018

Keywords

mass spectrometry
LC-MS/MS
HCD
ETD
EThcD
cross-linking
photo-oxidation
peroxyl radicals
AAPH
O-18 labeling

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10.1021/acs.jproteome.7b00881

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Mariotti, M., Leinisch, F., Leeming, D. J., Svensson, B., Davies, M. J., & Hagglund, P. (2018). Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation. Journal of Proteome Research, 17(6), 2017-2027. https://doi.org/10.1021/acs.jproteome.7b00881

Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation. / Mariotti, Michele; Leinisch, Fabian; Leeming, Diana Julie et al.

In: Journal of Proteome Research, Vol. 17, No. 6, 01.06.2018, p. 2017-2027.

Research output: Contribution to journal › Journal article › Research › peer-review

Mariotti, M, Leinisch, F, Leeming, DJ, Svensson, B, Davies, MJ & Hagglund, P 2018, 'Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation', Journal of Proteome Research, vol. 17, no. 6, pp. 2017-2027. https://doi.org/10.1021/acs.jproteome.7b00881

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title = "Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation",

keywords = "mass spectrometry, LC-MS/MS, HCD, ETD, EThcD, cross-linking, photo-oxidation, peroxyl radicals, AAPH, O-18 labeling",

author = "Michele Mariotti and Fabian Leinisch and Leeming, {Diana Julie} and Birte Svensson and Davies, {Michael J.} and Per Hagglund",

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doi = "10.1021/acs.jproteome.7b00881",

language = "English",

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AU - Mariotti, Michele

AU - Leinisch, Fabian

AU - Leeming, Diana Julie

AU - Svensson, Birte

AU - Davies, Michael J.

AU - Hagglund, Per

PY - 2018/6/1

Y1 - 2018/6/1

KW - mass spectrometry

KW - LC-MS/MS

KW - HCD

KW - ETD

KW - EThcD

KW - cross-linking

KW - photo-oxidation

KW - peroxyl radicals

KW - AAPH

KW - O-18 labeling

U2 - 10.1021/acs.jproteome.7b00881

DO - 10.1021/acs.jproteome.7b00881

M3 - Journal article

C2 - 29651848

SN - 1535-3893

VL - 17

SP - 2017

EP - 2027

JO - Journal of Proteome Research

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IS - 6

ER -

Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

Keywords

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Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using ¹⁸O Labeling and Optimized Tandem Mass Spectrometry Fragmentation