Lysyl oxidase in cancer research

Lara Perryman; Janine Terra Erler

doi:10.2217/fon.14.39

Lysyl oxidase in cancer research

30 Citations (Scopus)

Abstract

Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we will breakdown the process of cancer progression and the various roles that LOX plays has in the advancement of cancer. We will highlight why LOX is an exciting therapeutic target for the future.

Original language	English
Journal	Future Oncology
Volume	10
Issue number	9
Pages (from-to)	1709-17
Number of pages	9
ISSN	1479-6694
DOIs	https://doi.org/10.2217/fon.14.39
Publication status	Published - Aug 2014

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title = "Lysyl oxidase in cancer research",

abstract = "Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we will breakdown the process of cancer progression and the various roles that LOX plays has in the advancement of cancer. We will highlight why LOX is an exciting therapeutic target for the future.",

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AB - Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we will breakdown the process of cancer progression and the various roles that LOX plays has in the advancement of cancer. We will highlight why LOX is an exciting therapeutic target for the future.

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JO - Future Oncology

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Lysyl oxidase in cancer research

Abstract

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