Lysyl oxidase in cancer research

TY - JOUR

T1 - Lysyl oxidase in cancer research

AU - Perryman, Lara

AU - Erler, Janine Terra

PY - 2014/8

Y1 - 2014/8

N2 - Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we will breakdown the process of cancer progression and the various roles that LOX plays has in the advancement of cancer. We will highlight why LOX is an exciting therapeutic target for the future.

AB - Metastasis is the main reason for cancer-associated deaths and therapies are desperately needed to target the progression of cancer. Lysyl oxidase (LOX) plays a pivotal role in cancer progression, including metastasis, and is therefore is an attractive therapeutic target. In this review we will breakdown the process of cancer progression and the various roles that LOX plays has in the advancement of cancer. We will highlight why LOX is an exciting therapeutic target for the future.

U2 - 10.2217/fon.14.39

DO - 10.2217/fon.14.39

M3 - Review

C2 - 25145437

SN - 1479-6694

VL - 10

SP - 1709

EP - 1717

JO - Future Oncology

JF - Future Oncology

IS - 9

ER -