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Loop 7 of E2 enzymes: an ancestral conserved functional motif involved in the E2-mediated steps of the ubiquitination cascade
Elena Papaleo
, Nicola Casiraghi, Alberto Arrigoni, Marco Vanoni, Paola Coccetti, Luca De Gioia
Biomolecular Sciences
22
Citations (Scopus)
497
Downloads (Pure)
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Dive into the research topics of 'Loop 7 of E2 enzymes: an ancestral conserved functional motif involved in the E2-mediated steps of the ubiquitination cascade'. Together they form a unique fingerprint.
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Keyphrases
Ubiquitin
100%
Functional Motif
100%
Ubiquitination
100%
UBE2T
100%
Hydrophobic Interaction
33%
Three-class
33%
Interaction Network
33%
Ubiquitin System
33%
Ubiquitination Pathway
33%
Hydrophobic Residues
33%
Phosphorylation
33%
Associated Functions
33%
For Loop
33%
Ternary Complex
33%
Dynamic Properties
33%
Eukaryotic Cells
33%
Inactive Conformation
33%
Sequential Behavior
33%
Binary Complexes
33%
Main Determinants
33%
Tight
33%
Active Conformation
33%
System Control
33%
Protein Ubiquitination
33%
Catalytic Cleft
33%
Electrostatic Repulsion
33%
Cell Biology
33%
Biochemistry, Genetics and Molecular Biology
Enzyme
100%
Ubiquitination
100%
Ubiquitin
80%
Conformation
60%
Ternary Complex
20%
Ubiquitin-Conjugating Enzyme
20%