Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

Ram Dessau; Jette Marie Bangsborg; Tove P Ejlertsen Jensen; Klaus Hansen; Anne-Mette K Lebech; Christian Østergaard Andersen

Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

Translated title of the contribution: Laboratory diagnosis of infection caused by Borrelia burgdorferi

Ram Dessau, Jette Marie Bangsborg, Tove P Ejlertsen Jensen, Klaus Hansen, Anne-Mette K Lebech, Christian Østergaard Andersen

Department of Immunology and Microbiology

12 Citations (Scopus)

Abstract

The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.

Translated title of the contribution	Laboratory diagnosis of infection caused by Borrelia burgdorferi
Original language	Danish
Journal	Ugeskrift for Laeger
Volume	168
Issue number	34
Pages (from-to)	2805-7
Number of pages	3
ISSN	0041-5782
Publication status	Published - 2006

Cite this

@article{af3f9db8052042ce81c79fcae5c9576e,

title = "Laboratoriediagnostik af infektion for{\aa}rsaget af Borrelia burgdorferi",

abstract = "The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.",

keywords = "Antibodies, Bacterial, Blotting, Western, Borrelia burgdorferi, Enzyme-Linked Immunosorbent Assay, Humans, Lyme Disease, Lyme Neuroborreliosis, Serologic Tests",

author = "Ram Dessau and Bangsborg, {Jette Marie} and Jensen, {Tove P Ejlertsen} and Klaus Hansen and Lebech, {Anne-Mette K} and Andersen, {Christian {\O}stergaard}",

year = "2006",

language = "Dansk",

volume = "168",

pages = "2805--7",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "34",

}

TY - JOUR

T1 - Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

AU - Dessau, Ram

AU - Bangsborg, Jette Marie

AU - Jensen, Tove P Ejlertsen

AU - Hansen, Klaus

AU - Lebech, Anne-Mette K

AU - Andersen, Christian Østergaard

PY - 2006

Y1 - 2006

N2 - The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.

AB - The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.

KW - Antibodies, Bacterial

KW - Blotting, Western

KW - Borrelia burgdorferi

KW - Enzyme-Linked Immunosorbent Assay

KW - Humans

KW - Lyme Disease

KW - Lyme Neuroborreliosis

KW - Serologic Tests

M3 - Tidsskriftartikel

C2 - 16942701

SN - 0041-5782

VL - 168

SP - 2805

EP - 2807

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 34

ER -

Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

Abstract

Fingerprint

Cite this