Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

TY - JOUR

T1 - Laboratoriediagnostik af infektion forårsaget af Borrelia burgdorferi

AU - Dessau, Ram

AU - Bangsborg, Jette Marie

AU - Jensen, Tove P Ejlertsen

AU - Hansen, Klaus

AU - Lebech, Anne-Mette K

AU - Andersen, Christian Østergaard

PY - 2006

Y1 - 2006

N2 - The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.

AB - The laboratory diagnosis of Lyme disease in Denmark is reviewed with recommendations for serological testing. In Denmark the laboratory testing is performed with an ELISA technique. Most laboratories use an assay based on purified flagella antigen. The two-tier approach with Western Blot as confirmatory testing is not recommended since the contribution to the diagnostic specificity is only marginal. Predictive values of Lyme serology are presented, based on the estimated prevalence of the different stages of Lyme disease in Denmark.

KW - Antibodies, Bacterial

KW - Blotting, Western

KW - Borrelia burgdorferi

KW - Enzyme-Linked Immunosorbent Assay

KW - Humans

KW - Lyme Disease

KW - Lyme Neuroborreliosis

KW - Serologic Tests

M3 - Tidsskriftartikel

C2 - 16942701

SN - 0041-5782

VL - 168

SP - 2805

EP - 2807

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 34

ER -