Kliniske symptomer og patofysiologi ved migraene

Translated title of the contribution: Clinical symptoms and pathophysiology of migraine

P. Tfelt-Hansen, M. Ashina, J. Olesen, Peer Tfelt-Hansen, Messoud Ashina, Jes Olesen

    3 Citations (Scopus)

    Abstract

    Understanding of the pathophysiology of migraine attacks requires consideration of both symptoms and paraclinical investigations. During the aura phase, characteristic changes in regional cerebral blood flow (rCBF) can be observed. The headache is most likely a form of neurovascular pain. Nausea, photo- and phonophobia are probably elicited from the central nervous system. Positron emission tomography (PET) scans reveal specific changes in the brain stem. Allodynia, most likely caused by central sensitization, often develops during the attack. In conclusion, the migraine attack is a complex neurobiological and neurovascular process.
    Udgivelsesdato: 2008-Oct-6
    Translated title of the contributionClinical symptoms and pathophysiology of migraine
    Original languageDanish
    JournalUgeskrift for læger
    Volume170
    Issue number41
    Pages (from-to)3231-4
    Number of pages3
    ISSN0041-5782
    Publication statusPublished - 2008

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