Kliniske symptomer og patofysiologi ved migraene

P. Tfelt-Hansen, M. Ashina, J. Olesen, Peer Tfelt-Hansen, Messoud Ashina, Jes Olesen

    3 Citationer (Scopus)

    Abstract

    Understanding of the pathophysiology of migraine attacks requires consideration of both symptoms and paraclinical investigations. During the aura phase, characteristic changes in regional cerebral blood flow (rCBF) can be observed. The headache is most likely a form of neurovascular pain. Nausea, photo- and phonophobia are probably elicited from the central nervous system. Positron emission tomography (PET) scans reveal specific changes in the brain stem. Allodynia, most likely caused by central sensitization, often develops during the attack. In conclusion, the migraine attack is a complex neurobiological and neurovascular process.
    Udgivelsesdato: 2008-Oct-6
    Bidragets oversatte titelClinical symptoms and pathophysiology of migraine
    OriginalsprogDansk
    TidsskriftUgeskrift for læger
    Vol/bind170
    Udgave nummer41
    Sider (fra-til)3231-4
    Antal sider3
    ISSN0041-5782
    StatusUdgivet - 2008

    Citationsformater