Intrachiasmatic abscess caused by IgG4-related hypophysitis

Georgios F Hadjigeorgiou; Eva Løbner Lund; Lars Poulsgaard; Ulla Feldt-Rasmussen; Åse Krogh Rasmussen; Marianne Wegener; Kåre Fugleholm

doi:10.1007/s00701-017-3288-8

Intrachiasmatic abscess caused by IgG4-related hypophysitis

Georgios F Hadjigeorgiou, Eva Løbner Lund, Lars Poulsgaard, Ulla Feldt-Rasmussen, Åse Krogh Rasmussen, Marianne Wegener, Kåre Fugleholm

Department of Clinical Medicine

8 Citations (Scopus)

Abstract

INTRODUCTION: Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.

METHODS: In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.

RESULTS: The histologic findings were consistent with IgG4 hypophysitis.

CONCLUSION: This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.

Original language	English
Journal	Acta Neurochirurgica
Volume	159
Issue number	11
Pages (from-to)	2229-2233
Number of pages	5
ISSN	0001-6268
DOIs	https://doi.org/10.1007/s00701-017-3288-8
Publication status	Published - 1 Nov 2017

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abstract = "INTRODUCTION: Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.METHODS: In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.RESULTS: The histologic findings were consistent with IgG4 hypophysitis.CONCLUSION: This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.",

author = "Hadjigeorgiou, {Georgios F} and Lund, {Eva L{\o}bner} and Lars Poulsgaard and Ulla Feldt-Rasmussen and Rasmussen, {{\AA}se Krogh} and Marianne Wegener and K{\aa}re Fugleholm",

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T1 - Intrachiasmatic abscess caused by IgG4-related hypophysitis

AU - Hadjigeorgiou, Georgios F

AU - Lund, Eva Løbner

AU - Poulsgaard, Lars

AU - Feldt-Rasmussen, Ulla

AU - Rasmussen, Åse Krogh

AU - Wegener, Marianne

AU - Fugleholm, Kåre

PY - 2017/11/1

Y1 - 2017/11/1

N2 - INTRODUCTION: Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.METHODS: In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.RESULTS: The histologic findings were consistent with IgG4 hypophysitis.CONCLUSION: This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.

AB - INTRODUCTION: Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.METHODS: In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.RESULTS: The histologic findings were consistent with IgG4 hypophysitis.CONCLUSION: This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.

U2 - 10.1007/s00701-017-3288-8

DO - 10.1007/s00701-017-3288-8

M3 - Journal article

C2 - 28799078

SN - 0001-6268

VL - 159

SP - 2229

EP - 2233

JO - Acta Neurochirurgica

JF - Acta Neurochirurgica

IS - 11

ER -

Intrachiasmatic abscess caused by IgG4-related hypophysitis

Abstract

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