Intrachiasmatic abscess caused by IgG4-related hypophysitis

Georgios F Hadjigeorgiou; Eva Løbner Lund; Lars Poulsgaard; Ulla Feldt-Rasmussen; Åse Krogh Rasmussen; Marianne Wegener; Kåre Fugleholm

doi:10.1007/s00701-017-3288-8

Intrachiasmatic abscess caused by IgG4-related hypophysitis

Georgios F Hadjigeorgiou, Eva Løbner Lund, Lars Poulsgaard, Ulla Feldt-Rasmussen, Åse Krogh Rasmussen, Marianne Wegener, Kåre Fugleholm

Institut for Klinisk Medicin

8 Citationer (Scopus)

Abstract

INTRODUCTION: Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.

METHODS: In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.

RESULTS: The histologic findings were consistent with IgG4 hypophysitis.

CONCLUSION: This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.

Originalsprog	Engelsk
Tidsskrift	Acta Neurochirurgica
Vol/bind	159
Udgave nummer	11
Sider (fra-til)	2229-2233
Antal sider	5
ISSN	0001-6268
DOI	https://doi.org/10.1007/s00701-017-3288-8
Status	Udgivet - 1 nov. 2017

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10.1007/s00701-017-3288-8

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abstract = "INTRODUCTION: Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.METHODS: In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.RESULTS: The histologic findings were consistent with IgG4 hypophysitis.CONCLUSION: This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.",

author = "Hadjigeorgiou, {Georgios F} and Lund, {Eva L{\o}bner} and Lars Poulsgaard and Ulla Feldt-Rasmussen and Rasmussen, {{\AA}se Krogh} and Marianne Wegener and K{\aa}re Fugleholm",

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T1 - Intrachiasmatic abscess caused by IgG4-related hypophysitis

AU - Hadjigeorgiou, Georgios F

AU - Lund, Eva Løbner

AU - Poulsgaard, Lars

AU - Feldt-Rasmussen, Ulla

AU - Rasmussen, Åse Krogh

AU - Wegener, Marianne

AU - Fugleholm, Kåre

PY - 2017/11/1

Y1 - 2017/11/1

N2 - INTRODUCTION: Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.METHODS: In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.RESULTS: The histologic findings were consistent with IgG4 hypophysitis.CONCLUSION: This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.

AB - INTRODUCTION: Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported.METHODS: In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess.RESULTS: The histologic findings were consistent with IgG4 hypophysitis.CONCLUSION: This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.

U2 - 10.1007/s00701-017-3288-8

DO - 10.1007/s00701-017-3288-8

M3 - Journal article

C2 - 28799078

SN - 0001-6268

VL - 159

SP - 2229

EP - 2233

JO - Acta Neurochirurgica

JF - Acta Neurochirurgica

IS - 11

ER -

Intrachiasmatic abscess caused by IgG4-related hypophysitis

Abstract

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