Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies

Hélène Chabas; Stineke van Houte; Nina Molin Høyland-Kroghsbo; Angus Buckling; Edze R Westra

doi:10.1098/rspb.2016.0721

Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies

Hélène Chabas, Stineke van Houte, Nina Molin Høyland-Kroghsbo, Angus Buckling, Edze R Westra

19 Citations (Scopus)

Abstract

Migration of hosts and parasites can have a profound impact on host-parasite ecological and evolutionary interactions. Using the bacterium Pseudomonas aeruginosa UCBPP-PA14 and its phage DMS3vir, we here show that immigration of naive hosts into coevolving populations of hosts and parasites can influence the mechanistic basis underlying host defence evolution. Specifically, we found that at high levels of bacterial immigration, bacteria switched from clustered regularly interspaced short palindromic repeats (CRISPR-Cas) to surface modification-mediated defence. This effect emerges from an increase in the force of infection, which tips the balance from CRISPR to surface modification-based defence owing to the induced and fixed fitness costs associated with these mechanisms, respectively.

Original language	English
Journal	Proceedings. Biological sciences / The Royal Society
Volume	283
Issue number	1837
Number of pages	6
ISSN	0962-8452
DOIs	https://doi.org/10.1098/rspb.2016.0721
Publication status	Published - 31 Aug 2016
Externally published	Yes

Keywords

Journal Article

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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AU - Chabas, Hélène

AU - van Houte, Stineke

AU - Høyland-Kroghsbo, Nina Molin

AU - Buckling, Angus

AU - Westra, Edze R

PY - 2016/8/31

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AB - Migration of hosts and parasites can have a profound impact on host-parasite ecological and evolutionary interactions. Using the bacterium Pseudomonas aeruginosa UCBPP-PA14 and its phage DMS3vir, we here show that immigration of naive hosts into coevolving populations of hosts and parasites can influence the mechanistic basis underlying host defence evolution. Specifically, we found that at high levels of bacterial immigration, bacteria switched from clustered regularly interspaced short palindromic repeats (CRISPR-Cas) to surface modification-mediated defence. This effect emerges from an increase in the force of infection, which tips the balance from CRISPR to surface modification-based defence owing to the induced and fixed fitness costs associated with these mechanisms, respectively.

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Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies

Abstract

Keywords

UN SDGs

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