Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies

Hélène Chabas; Stineke van Houte; Nina Molin Høyland-Kroghsbo; Angus Buckling; Edze R Westra

doi:10.1098/rspb.2016.0721

Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies

Hélène Chabas, Stineke van Houte, Nina Molin Høyland-Kroghsbo, Angus Buckling, Edze R Westra

19 Citationer (Scopus)

Abstract

Migration of hosts and parasites can have a profound impact on host-parasite ecological and evolutionary interactions. Using the bacterium Pseudomonas aeruginosa UCBPP-PA14 and its phage DMS3vir, we here show that immigration of naive hosts into coevolving populations of hosts and parasites can influence the mechanistic basis underlying host defence evolution. Specifically, we found that at high levels of bacterial immigration, bacteria switched from clustered regularly interspaced short palindromic repeats (CRISPR-Cas) to surface modification-mediated defence. This effect emerges from an increase in the force of infection, which tips the balance from CRISPR to surface modification-based defence owing to the induced and fixed fitness costs associated with these mechanisms, respectively.

Originalsprog	Engelsk
Tidsskrift	Proceedings. Biological sciences / The Royal Society
Vol/bind	283
Udgave nummer	1837
Antal sider	6
ISSN	0962-8452
DOI	https://doi.org/10.1098/rspb.2016.0721
Status	Udgivet - 31 aug. 2016
Udgivet eksternt	Ja

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10.1098/rspb.2016.0721

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AU - Chabas, Hélène

AU - van Houte, Stineke

AU - Høyland-Kroghsbo, Nina Molin

AU - Buckling, Angus

AU - Westra, Edze R

PY - 2016/8/31

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N2 - Migration of hosts and parasites can have a profound impact on host-parasite ecological and evolutionary interactions. Using the bacterium Pseudomonas aeruginosa UCBPP-PA14 and its phage DMS3vir, we here show that immigration of naive hosts into coevolving populations of hosts and parasites can influence the mechanistic basis underlying host defence evolution. Specifically, we found that at high levels of bacterial immigration, bacteria switched from clustered regularly interspaced short palindromic repeats (CRISPR-Cas) to surface modification-mediated defence. This effect emerges from an increase in the force of infection, which tips the balance from CRISPR to surface modification-based defence owing to the induced and fixed fitness costs associated with these mechanisms, respectively.

AB - Migration of hosts and parasites can have a profound impact on host-parasite ecological and evolutionary interactions. Using the bacterium Pseudomonas aeruginosa UCBPP-PA14 and its phage DMS3vir, we here show that immigration of naive hosts into coevolving populations of hosts and parasites can influence the mechanistic basis underlying host defence evolution. Specifically, we found that at high levels of bacterial immigration, bacteria switched from clustered regularly interspaced short palindromic repeats (CRISPR-Cas) to surface modification-mediated defence. This effect emerges from an increase in the force of infection, which tips the balance from CRISPR to surface modification-based defence owing to the induced and fixed fitness costs associated with these mechanisms, respectively.

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Immigration of susceptible hosts triggers the evolution of alternative parasite defence strategies

Abstract

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