Hemodynamic stress echocardiography in patients supported with a continuous-flow left ventricular assist device

Mads Andersen; Finn Gustafsson; Per Lav Madsen; Patrice Brassard; Anette Schophuus Jensen; Niels Secher; Christian Hassager; Nikolai Nordsborg; Jacob Eifer Møller

doi:10.1016/j.jcmg.2010.06.007

Hemodynamic stress echocardiography in patients supported with a continuous-flow left ventricular assist device

Mads Andersen, Finn Gustafsson, Per Lav Madsen, Patrice Brassard, Anette Schophuus Jensen, Niels Secher, Christian Hassager, Nikolai Nordsborg, Jacob Eifer Møller

23 Citations (Scopus)

Abstract

Functional assessment of continuous-flow left ventricular assist devices (LVADs) is usually performed with the patient at rest. This study compared echocardiographic indices of contraction and filling pressure with invasive measures in 12 ambulatory LVAD patients undergoing symptom-limited bicycle exercise. Exercise induced an increase in cardiac output, systolic pulmonary artery pressure, and diastolic pulmonary artery pressure. Although no changes in left ventricular dimensions or fractional shortening were seen on echocardiography, systolic mitral annular motion (S') increased significantly (in parallel with cardiac output) and diastolic E/e' ratio decreased (correlating inversely with diastolic pulmonary artery pressure). These findings emphasize the potential role of exercise echocardiography in studying exercise hemodynamics in LVAD patients.

Original language	English
Journal	JACC - Cardiovascular Imaging
Volume	3
Issue number	8
Pages (from-to)	854-859
Number of pages	6
ISSN	1936-878X
DOIs	https://doi.org/10.1016/j.jcmg.2010.06.007
Publication status	Published - Aug 2010
Externally published	Yes

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title = "Hemodynamic stress echocardiography in patients supported with a continuous-flow left ventricular assist device",

abstract = "Functional assessment of continuous-flow left ventricular assist devices (LVADs) is usually performed with the patient at rest. This study compared echocardiographic indices of contraction and filling pressure with invasive measures in 12 ambulatory LVAD patients undergoing symptom-limited bicycle exercise. Exercise induced an increase in cardiac output, systolic pulmonary artery pressure, and diastolic pulmonary artery pressure. Although no changes in left ventricular dimensions or fractional shortening were seen on echocardiography, systolic mitral annular motion (S') increased significantly (in parallel with cardiac output) and diastolic E/e' ratio decreased (correlating inversely with diastolic pulmonary artery pressure). These findings emphasize the potential role of exercise echocardiography in studying exercise hemodynamics in LVAD patients.",

author = "Mads Andersen and Finn Gustafsson and {Lav Madsen}, Per and Patrice Brassard and Jensen, {Anette Schophuus} and Niels Secher and Christian Hassager and Nikolai Nordsborg and M{\o}ller, {Jacob Eifer}",

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T1 - Hemodynamic stress echocardiography in patients supported with a continuous-flow left ventricular assist device

AU - Andersen, Mads

AU - Gustafsson, Finn

AU - Lav Madsen, Per

AU - Brassard, Patrice

AU - Jensen, Anette Schophuus

AU - Secher, Niels

AU - Hassager, Christian

AU - Nordsborg, Nikolai

AU - Møller, Jacob Eifer

N1 - CURIS 2010 5200 110

PY - 2010/8

Y1 - 2010/8

N2 - Functional assessment of continuous-flow left ventricular assist devices (LVADs) is usually performed with the patient at rest. This study compared echocardiographic indices of contraction and filling pressure with invasive measures in 12 ambulatory LVAD patients undergoing symptom-limited bicycle exercise. Exercise induced an increase in cardiac output, systolic pulmonary artery pressure, and diastolic pulmonary artery pressure. Although no changes in left ventricular dimensions or fractional shortening were seen on echocardiography, systolic mitral annular motion (S') increased significantly (in parallel with cardiac output) and diastolic E/e' ratio decreased (correlating inversely with diastolic pulmonary artery pressure). These findings emphasize the potential role of exercise echocardiography in studying exercise hemodynamics in LVAD patients.

AB - Functional assessment of continuous-flow left ventricular assist devices (LVADs) is usually performed with the patient at rest. This study compared echocardiographic indices of contraction and filling pressure with invasive measures in 12 ambulatory LVAD patients undergoing symptom-limited bicycle exercise. Exercise induced an increase in cardiac output, systolic pulmonary artery pressure, and diastolic pulmonary artery pressure. Although no changes in left ventricular dimensions or fractional shortening were seen on echocardiography, systolic mitral annular motion (S') increased significantly (in parallel with cardiac output) and diastolic E/e' ratio decreased (correlating inversely with diastolic pulmonary artery pressure). These findings emphasize the potential role of exercise echocardiography in studying exercise hemodynamics in LVAD patients.

U2 - 10.1016/j.jcmg.2010.06.007

DO - 10.1016/j.jcmg.2010.06.007

M3 - Journal article

C2 - 20705267

SN - 1936-878X

VL - 3

SP - 854

EP - 859

JO - J A C C: Cardiovascular Imaging

JF - J A C C: Cardiovascular Imaging

IS - 8

ER -

Hemodynamic stress echocardiography in patients supported with a continuous-flow left ventricular assist device

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