Harnessing transcription for bioproduction in cyanobacteria

Karin Stensjö, Konstantinos Vavitsas, Taina Tyystjärvi

15 Citations (Scopus)

Abstract

Sustainable production of biofuels and other valuable compounds is one of our future challenges. One tempting possibility is to use photosynthetic cyanobacteria as production factories. Currently, tools for genetic engineering of cyanobacteria are not good enough to exploit the full potential of cyanobacteria. A wide variety of expression systems will be required to adjust both the expression of heterologous enzyme(s) and metabolic routes to the best possible balance, allowing the optimal production of a particular substance. In bacteria, transcription, especially the initiation of transcription, has a central role in adjusting gene expression and thus also metabolic fluxes of cells according to environmental cues. Here we summarize the recent progress in developing tools for efficient cyanofactories, focusing especially on transcriptional regulation.

Original languageEnglish
JournalPhysiologia Plantarum
Volume162
Issue number2
Pages (from-to)148-155
Number of pages8
ISSN0031-9317
DOIs
Publication statusPublished - 1 Feb 2018

Keywords

  • Journal Article

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