Harnessing transcription for bioproduction in cyanobacteria

Karin Stensjö, Konstantinos Vavitsas, Taina Tyystjärvi

15 Citationer (Scopus)

Abstract

Sustainable production of biofuels and other valuable compounds is one of our future challenges. One tempting possibility is to use photosynthetic cyanobacteria as production factories. Currently, tools for genetic engineering of cyanobacteria are not good enough to exploit the full potential of cyanobacteria. A wide variety of expression systems will be required to adjust both the expression of heterologous enzyme(s) and metabolic routes to the best possible balance, allowing the optimal production of a particular substance. In bacteria, transcription, especially the initiation of transcription, has a central role in adjusting gene expression and thus also metabolic fluxes of cells according to environmental cues. Here we summarize the recent progress in developing tools for efficient cyanofactories, focusing especially on transcriptional regulation.

OriginalsprogEngelsk
TidsskriftPhysiologia Plantarum
Vol/bind162
Udgave nummer2
Sider (fra-til)148-155
Antal sider8
ISSN0031-9317
DOI
StatusUdgivet - 1 feb. 2018

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