GlycoViewer: A tool for visual summary and comparative analysis of the glycome

Hiren J. Joshi; Claus Wilhelm von der Lieth; Nicolle H. Packer; Marc R. Wilkins

doi:10.1093/nar/gkq446

GlycoViewer: A tool for visual summary and comparative analysis of the glycome

Hiren J. Joshi, Claus Wilhelm von der Lieth, Nicolle H. Packer, Marc R. Wilkins^*

^*Corresponding author for this work

Glycomics Program

11 Citations (Scopus)

Abstract

The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can summarize up to hundreds of structures in a single figure. This allows unique, high-level views to be generated of glycans from one protein, from a cell, a tissue or a whole organism. Use of the tool is illustrated in the analysis of normal and diseaseassociated glycans from the human glycoproteome.

Original language	English
Article number	gkq446
Journal	Nucleic Acids Research
Volume	38
Issue number	SUPPL. 2
Pages (from-to)	W667-W670
ISSN	0305-1048
DOIs	https://doi.org/10.1093/nar/gkq446
Publication status	Published - 25 May 2010

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abstract = "The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can summarize up to hundreds of structures in a single figure. This allows unique, high-level views to be generated of glycans from one protein, from a cell, a tissue or a whole organism. Use of the tool is illustrated in the analysis of normal and diseaseassociated glycans from the human glycoproteome.",

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GlycoViewer: A tool for visual summary and comparative analysis of the glycome

Abstract

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