GlycoViewer: A tool for visual summary and comparative analysis of the glycome

Hiren J. Joshi; Claus Wilhelm von der Lieth; Nicolle H. Packer; Marc R. Wilkins

doi:10.1093/nar/gkq446

GlycoViewer: A tool for visual summary and comparative analysis of the glycome

Hiren J. Joshi, Claus Wilhelm von der Lieth, Nicolle H. Packer, Marc R. Wilkins^*

^*Corresponding author af dette arbejde

Glycomics Program

11 Citationer (Scopus)

Abstract

The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can summarize up to hundreds of structures in a single figure. This allows unique, high-level views to be generated of glycans from one protein, from a cell, a tissue or a whole organism. Use of the tool is illustrated in the analysis of normal and diseaseassociated glycans from the human glycoproteome.

Originalsprog	Engelsk
Artikelnummer	gkq446
Tidsskrift	Nucleic Acids Research
Vol/bind	38
Udgave nummer	SUPPL. 2
Sider (fra-til)	W667-W670
ISSN	0305-1048
DOI	https://doi.org/10.1093/nar/gkq446
Status	Udgivet - 25 maj 2010

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title = "GlycoViewer: A tool for visual summary and comparative analysis of the glycome",

abstract = "The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can summarize up to hundreds of structures in a single figure. This allows unique, high-level views to be generated of glycans from one protein, from a cell, a tissue or a whole organism. Use of the tool is illustrated in the analysis of normal and diseaseassociated glycans from the human glycoproteome.",

author = "Joshi, {Hiren J.} and {von der Lieth}, {Claus Wilhelm} and Packer, {Nicolle H.} and Wilkins, {Marc R.}",

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AU - Joshi, Hiren J.

AU - von der Lieth, Claus Wilhelm

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AU - Wilkins, Marc R.

PY - 2010/5/25

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AB - The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can summarize up to hundreds of structures in a single figure. This allows unique, high-level views to be generated of glycans from one protein, from a cell, a tissue or a whole organism. Use of the tool is illustrated in the analysis of normal and diseaseassociated glycans from the human glycoproteome.

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GlycoViewer: A tool for visual summary and comparative analysis of the glycome

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