TY - JOUR
T1 - Functions of myosin motors tailored for parasitism
AU - Mueller, Christina
AU - Graindorge, Arnault
AU - Soldati-Favre, Dominique
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Myosin motors are one of the largest protein families in eukaryotes that exhibit divergent cellular functions. Their roles in protozoans, a diverse group of anciently diverged, single celled organisms with many prominent members known to be parasitic and to cause diseases in human and livestock, are largely unknown. In the recent years many different approaches, among them whole genome sequencing, phylogenetic analyses and functional studies have increased our understanding on the distribution, protein architecture and function of unconventional myosin motors in protozoan parasites. In Apicomplexa, myosins turn out to be highly specialized and to exhibit unique functions tailored to accommodate the lifestyle of these parasites.
AB - Myosin motors are one of the largest protein families in eukaryotes that exhibit divergent cellular functions. Their roles in protozoans, a diverse group of anciently diverged, single celled organisms with many prominent members known to be parasitic and to cause diseases in human and livestock, are largely unknown. In the recent years many different approaches, among them whole genome sequencing, phylogenetic analyses and functional studies have increased our understanding on the distribution, protein architecture and function of unconventional myosin motors in protozoan parasites. In Apicomplexa, myosins turn out to be highly specialized and to exhibit unique functions tailored to accommodate the lifestyle of these parasites.
U2 - 10.1016/j.mib.2017.11.003
DO - 10.1016/j.mib.2017.11.003
M3 - Review
C2 - 29161623
AN - SCOPUS:85034597816
SN - 1369-5274
VL - 40
SP - 113
EP - 122
JO - Current Opinion in Microbiology
JF - Current Opinion in Microbiology
ER -
