Abstract
During recent years the importance of neuro-glial interactions for the maintenance of the normal function of the central and peripheral nervous systems has been fully recognized [10, 8]. The restricted perspective on the role of the glial cells to provide only metabolic support and uptake of K+ions and neurotransmitters no longer agrees with data that reveal their participation in synaptic transmission, long-term potentiation, synaptic plasticity, and the development of neuronal pathologies. As a result the new concept of the tripartite synapse has emerged [23], and studies of the interaction between the neurons and glial cells have become an important area of neurophysiology and cell biophysics.
Original language | English |
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Title of host publication | Biosimulation in Biomedical Research, Health Care and Drug Development |
Editors | Erik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan |
Publisher | Springer |
Publication date | 1 Jan 2012 |
Pages | 133-151 |
Chapter | 6 |
ISBN (Print) | 978-3-7091-0417-0 |
DOIs | |
Publication status | Published - 1 Jan 2012 |