Functional Modeling of Neural-Glia Interaction

D.E. Postnov, N.A. Brazhe, Olga Sosnovtseva

2 Citations (Scopus)

Abstract

During recent years the importance of neuro-glial interactions for the maintenance of the normal function of the central and peripheral nervous systems has been fully recognized [10, 8]. The restricted perspective on the role of the glial cells to provide only metabolic support and uptake of K+ions and neurotransmitters no longer agrees with data that reveal their participation in synaptic transmission, long-term potentiation, synaptic plasticity, and the development of neuronal pathologies. As a result the new concept of the tripartite synapse has emerged [23], and studies of the interaction between the neurons and glial cells have become an important area of neurophysiology and cell biophysics.

Original languageEnglish
Title of host publicationBiosimulation in Biomedical Research, Health Care and Drug Development
EditorsErik Mosekilde, Olga Sosnovtseva, Amin Rostami-Hodjegan
PublisherSpringer
Publication date1 Jan 2012
Pages133-151
Chapter6
ISBN (Print)978-3-7091-0417-0
DOIs
Publication statusPublished - 1 Jan 2012

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