TY - JOUR
T1 - Fruit and vegetable intake and risk of acute coronary syndrome
AU - Hansen, Louise
AU - Dragsted, Lars Ove
AU - Olsen, Anja
AU - Christensen, Jane
AU - Tjønneland, Anne
AU - Schmidt, Erik Berg
AU - Overvad, Kim
PY - 2010/7
Y1 - 2010/7
N2 - Prospective epidemiological studies have reported that a higher fruit and vegetable intake is associated with a lower risk of CHD. The aim of the present study was to examine associations between fruit and vegetable consumption, in particular the subgroupings citrus fruits, apples and cruciferous vegetables, and the risk of acute coronary syndrome (ACS). During a median follow-up of 77 years, 1075 incident ACS cases were identified among 53383 men and women, aged 50-64 years at recruitment into the Diet, Cancer and Health cohort study in 1993-7. Fruit and vegetable intake was estimated from a validated FFQ, and ACS incidence rate ratios (IRR) were estimated using Cox proportional hazards models. Overall, a tendency towards a lower risk of ACS was observed for both men and women with higher fruit and vegetable consumption. For men, we found an inverse association for apple intake (IRR per 25g/d: 097; 95% CI 094, 099). This association was also seen among women, albeit borderline significant. However, a higher risk was seen among women with higher fruit juice intake (IRR per 25g/d: 104; 95% CI 100, 108). The present results provide some support for previously observed inverse associations between fresh fruit intake, particularly apples, and ACS risk.
AB - Prospective epidemiological studies have reported that a higher fruit and vegetable intake is associated with a lower risk of CHD. The aim of the present study was to examine associations between fruit and vegetable consumption, in particular the subgroupings citrus fruits, apples and cruciferous vegetables, and the risk of acute coronary syndrome (ACS). During a median follow-up of 77 years, 1075 incident ACS cases were identified among 53383 men and women, aged 50-64 years at recruitment into the Diet, Cancer and Health cohort study in 1993-7. Fruit and vegetable intake was estimated from a validated FFQ, and ACS incidence rate ratios (IRR) were estimated using Cox proportional hazards models. Overall, a tendency towards a lower risk of ACS was observed for both men and women with higher fruit and vegetable consumption. For men, we found an inverse association for apple intake (IRR per 25g/d: 097; 95% CI 094, 099). This association was also seen among women, albeit borderline significant. However, a higher risk was seen among women with higher fruit juice intake (IRR per 25g/d: 104; 95% CI 100, 108). The present results provide some support for previously observed inverse associations between fresh fruit intake, particularly apples, and ACS risk.
U2 - 10.1017/S0007114510000462
DO - 10.1017/S0007114510000462
M3 - Journal article
C2 - 20178672
SN - 0007-1145
VL - 104
SP - 248
EP - 255
JO - British Journal of Nutrition
JF - British Journal of Nutrition
IS - 2
ER -