Fruit and vegetable intake and risk of acute coronary syndrome

Louise Hansen, Lars Ove Dragsted, Anja Olsen, Jane Christensen, Anne Tjønneland, Erik Berg Schmidt, Kim Overvad

    36 Citationer (Scopus)

    Abstract

    Prospective epidemiological studies have reported that a higher fruit and vegetable intake is associated with a lower risk of CHD. The aim of the present study was to examine associations between fruit and vegetable consumption, in particular the subgroupings citrus fruits, apples and cruciferous vegetables, and the risk of acute coronary syndrome (ACS). During a median follow-up of 77 years, 1075 incident ACS cases were identified among 53383 men and women, aged 50-64 years at recruitment into the Diet, Cancer and Health cohort study in 1993-7. Fruit and vegetable intake was estimated from a validated FFQ, and ACS incidence rate ratios (IRR) were estimated using Cox proportional hazards models. Overall, a tendency towards a lower risk of ACS was observed for both men and women with higher fruit and vegetable consumption. For men, we found an inverse association for apple intake (IRR per 25g/d: 097; 95% CI 094, 099). This association was also seen among women, albeit borderline significant. However, a higher risk was seen among women with higher fruit juice intake (IRR per 25g/d: 104; 95% CI 100, 108). The present results provide some support for previously observed inverse associations between fresh fruit intake, particularly apples, and ACS risk.

    OriginalsprogEngelsk
    TidsskriftBritish Journal of Nutrition
    Vol/bind104
    Udgave nummer2
    Sider (fra-til)248-255
    Antal sider8
    ISSN0007-1145
    DOI
    StatusUdgivet - jul. 2010

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