Forskelle på ordinationsmønstret af analgetika ved behandling af cancersmerter på seks danske smertebehandlingsenheder

Anne Estrup Olesen; Line Jarvig; Ole Bo Hansen; Jette Højsted; Niels-Henrik Jensen; Torsten Jonsson; Per Sjøgren; Nan Margrethe Sonne; Jacob Thorsted Sørensen; Lona L Christrup

Forskelle på ordinationsmønstret af analgetika ved behandling af cancersmerter på seks danske smertebehandlingsenheder

Translated title of the contribution: Differences in the prescription of analgesics in the treatment of cancer pain in six Danish pain treatment units

Anne Estrup Olesen, Line Jarvig, Ole Bo Hansen, Jette Højsted, Niels-Henrik Jensen, Torsten Jonsson, Per Sjøgren, Nan Margrethe Sonne, Jacob Thorsted Sørensen, Lona L Christrup

Department of Biomedical Sciences

1 Citation (Scopus)

Abstract

30-40% of cancer patients suffer from pain at diagnosis while 70-80% of patients at progressed stages of the disease suffer from pain. Background pain is treated with long-acting opioids. Breakthrough pain can be treated with shorter acting non-opioid analgesics or opioids. The aim of this study was to describe the medical treatment of pain in cancer patients in connection with six Danish hospital units with special expertise in pain treatment. Differences in the prescription of analgesics were studied. The study was performed as a cross section study of prescribed analgesics. Data was collected by reviewing medical records. The study included 347 patients. A total of 278 patients out of 347 were treated with opioids for background pains. A significant difference was found (P < 0.001) in the frequency of prescribing morphine, oxycodone and fentanyl. For the treatment of background pain secondary analgesics were prescribed for 40% of the patients while 50% of the patients were treated with paracetamol and/or NSAID. According to the medical records 79% of the patients were prescribed analgesics for breakthrough pain. 73% of the 347 patients had strong opioids prescribed for breakthrough pain. For the treatment of background pain opioids were prescribed for the majority of the cancer patients. Morphine and oxycodone were prescribed most frequently. Secondary analgesics and paracetamol and/or NSAID were also prescribed for background pain. The strong opioids were prescribed for the treatment of breakthrough pain. Differences in the prescription of analgesics between the six hospital units were observed in this study.

Translated title of the contribution	Differences in the prescription of analgesics in the treatment of cancer pain in six Danish pain treatment units
Original language	Danish
Journal	Ugeskrift for læger
Volume	169
Issue number	21
Pages (from-to)	2024-9
ISSN	0041-5782
Publication status	Published - 2007

Keywords

Former Faculty of Pharmaceutical Sciences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Forskelle p{\aa} ordinationsm{\o}nstret af analgetika ved behandling af cancersmerter p{\aa} seks danske smertebehandlingsenheder",

abstract = "30-40% of cancer patients suffer from pain at diagnosis while 70-80% of patients at progressed stages of the disease suffer from pain. Background pain is treated with long-acting opioids. Breakthrough pain can be treated with shorter acting non-opioid analgesics or opioids. The aim of this study was to describe the medical treatment of pain in cancer patients in connection with six Danish hospital units with special expertise in pain treatment. Differences in the prescription of analgesics were studied. The study was performed as a cross section study of prescribed analgesics. Data was collected by reviewing medical records. The study included 347 patients. A total of 278 patients out of 347 were treated with opioids for background pains. A significant difference was found (P < 0.001) in the frequency of prescribing morphine, oxycodone and fentanyl. For the treatment of background pain secondary analgesics were prescribed for 40% of the patients while 50% of the patients were treated with paracetamol and/or NSAID. According to the medical records 79% of the patients were prescribed analgesics for breakthrough pain. 73% of the 347 patients had strong opioids prescribed for breakthrough pain. For the treatment of background pain opioids were prescribed for the majority of the cancer patients. Morphine and oxycodone were prescribed most frequently. Secondary analgesics and paracetamol and/or NSAID were also prescribed for background pain. The strong opioids were prescribed for the treatment of breakthrough pain. Differences in the prescription of analgesics between the six hospital units were observed in this study.",

keywords = "Det tidligere Farmaceutiske Fakultet",

author = "Olesen, {Anne Estrup} and Line Jarvig and Hansen, {Ole Bo} and Jette H{\o}jsted and Niels-Henrik Jensen and Torsten Jonsson and Per Sj{\o}gren and Sonne, {Nan Margrethe} and S{\o}rensen, {Jacob Thorsted} and Christrup, {Lona L}",

note = "Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Sectional Studies; Denmark; Drug Utilization Review; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Pain Clinics; Physician's Practice Patterns; Prescriptions, Drug",

year = "2007",

language = "Dansk",

volume = "169",

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T1 - Forskelle på ordinationsmønstret af analgetika ved behandling af cancersmerter på seks danske smertebehandlingsenheder

AU - Olesen, Anne Estrup

AU - Jarvig, Line

AU - Hansen, Ole Bo

AU - Højsted, Jette

AU - Jensen, Niels-Henrik

AU - Jonsson, Torsten

AU - Sjøgren, Per

AU - Sonne, Nan Margrethe

AU - Sørensen, Jacob Thorsted

AU - Christrup, Lona L

N1 - Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cross-Sectional Studies; Denmark; Drug Utilization Review; Female; Humans; Male; Middle Aged; Neoplasms; Pain; Pain Clinics; Physician's Practice Patterns; Prescriptions, Drug

PY - 2007

Y1 - 2007

N2 - 30-40% of cancer patients suffer from pain at diagnosis while 70-80% of patients at progressed stages of the disease suffer from pain. Background pain is treated with long-acting opioids. Breakthrough pain can be treated with shorter acting non-opioid analgesics or opioids. The aim of this study was to describe the medical treatment of pain in cancer patients in connection with six Danish hospital units with special expertise in pain treatment. Differences in the prescription of analgesics were studied. The study was performed as a cross section study of prescribed analgesics. Data was collected by reviewing medical records. The study included 347 patients. A total of 278 patients out of 347 were treated with opioids for background pains. A significant difference was found (P < 0.001) in the frequency of prescribing morphine, oxycodone and fentanyl. For the treatment of background pain secondary analgesics were prescribed for 40% of the patients while 50% of the patients were treated with paracetamol and/or NSAID. According to the medical records 79% of the patients were prescribed analgesics for breakthrough pain. 73% of the 347 patients had strong opioids prescribed for breakthrough pain. For the treatment of background pain opioids were prescribed for the majority of the cancer patients. Morphine and oxycodone were prescribed most frequently. Secondary analgesics and paracetamol and/or NSAID were also prescribed for background pain. The strong opioids were prescribed for the treatment of breakthrough pain. Differences in the prescription of analgesics between the six hospital units were observed in this study.

AB - 30-40% of cancer patients suffer from pain at diagnosis while 70-80% of patients at progressed stages of the disease suffer from pain. Background pain is treated with long-acting opioids. Breakthrough pain can be treated with shorter acting non-opioid analgesics or opioids. The aim of this study was to describe the medical treatment of pain in cancer patients in connection with six Danish hospital units with special expertise in pain treatment. Differences in the prescription of analgesics were studied. The study was performed as a cross section study of prescribed analgesics. Data was collected by reviewing medical records. The study included 347 patients. A total of 278 patients out of 347 were treated with opioids for background pains. A significant difference was found (P < 0.001) in the frequency of prescribing morphine, oxycodone and fentanyl. For the treatment of background pain secondary analgesics were prescribed for 40% of the patients while 50% of the patients were treated with paracetamol and/or NSAID. According to the medical records 79% of the patients were prescribed analgesics for breakthrough pain. 73% of the 347 patients had strong opioids prescribed for breakthrough pain. For the treatment of background pain opioids were prescribed for the majority of the cancer patients. Morphine and oxycodone were prescribed most frequently. Secondary analgesics and paracetamol and/or NSAID were also prescribed for background pain. The strong opioids were prescribed for the treatment of breakthrough pain. Differences in the prescription of analgesics between the six hospital units were observed in this study.

KW - Det tidligere Farmaceutiske Fakultet

M3 - Tidsskriftartikel

C2 - 17553385

SN - 0041-5782

VL - 169

SP - 2024

EP - 2029

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 21

ER -

Forskelle på ordinationsmønstret af analgetika ved behandling af cancersmerter på seks danske smertebehandlingsenheder

Abstract

Keywords

UN SDGs

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