Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples

Henrik Jensen; Jesper Østergaard

doi:10.1021/ja100484d

Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples

30 Citations (Scopus)

Abstract

Chemical Figure Presented Flow Induced Dispersion Analysis (FIDA) is presented as a new approach to characterize noncovalent Interactions. The new method only requires nanollter samples, is easy to implement, and also provides diffusivities of the free analyte and the formed complex. The technique is based on signal analysis of temporal variances obtained for pressure driven flows in micrometer sized fused silica capillaries.

Original language	English
Journal	Journal of the American Chemical Society
Volume	132
Issue number	12
Pages (from-to)	4070-4071
ISSN	0002-7863
DOIs	https://doi.org/10.1021/ja100484d
Publication status	Published - 31 Mar 2010

Keywords

Former Faculty of Pharmaceutical Sciences

Access to Document

10.1021/ja100484d

Cite this

@article{00486ce056b511df928f000ea68e967b,

title = "Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples",

abstract = "Chemical Figure Presented Flow Induced Dispersion Analysis (FIDA) is presented as a new approach to characterize noncovalent Interactions. The new method only requires nanollter samples, is easy to implement, and also provides diffusivities of the free analyte and the formed complex. The technique is based on signal analysis of temporal variances obtained for pressure driven flows in micrometer sized fused silica capillaries.",

keywords = "Former Faculty of Pharmaceutical Sciences",

author = "Henrik Jensen and Jesper {\O}stergaard",

year = "2010",

month = mar,

day = "31",

doi = "10.1021/ja100484d",

language = "English",

volume = "132",

pages = "4070--4071",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "ACS Publications",

number = "12",

}

TY - JOUR

T1 - Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples

AU - Jensen, Henrik

AU - Østergaard, Jesper

PY - 2010/3/31

Y1 - 2010/3/31

N2 - Chemical Figure Presented Flow Induced Dispersion Analysis (FIDA) is presented as a new approach to characterize noncovalent Interactions. The new method only requires nanollter samples, is easy to implement, and also provides diffusivities of the free analyte and the formed complex. The technique is based on signal analysis of temporal variances obtained for pressure driven flows in micrometer sized fused silica capillaries.

AB - Chemical Figure Presented Flow Induced Dispersion Analysis (FIDA) is presented as a new approach to characterize noncovalent Interactions. The new method only requires nanollter samples, is easy to implement, and also provides diffusivities of the free analyte and the formed complex. The technique is based on signal analysis of temporal variances obtained for pressure driven flows in micrometer sized fused silica capillaries.

KW - Former Faculty of Pharmaceutical Sciences

U2 - 10.1021/ja100484d

DO - 10.1021/ja100484d

M3 - Journal article

C2 - 20201527

SN - 0002-7863

VL - 132

SP - 4070

EP - 4071

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 12

ER -

Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples

Abstract

Keywords

Access to Document

Fingerprint

Cite this