Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples

Henrik Jensen; Jesper Østergaard

doi:10.1021/ja100484d

Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples

30 Citationer (Scopus)

Abstract

Chemical Figure Presented Flow Induced Dispersion Analysis (FIDA) is presented as a new approach to characterize noncovalent Interactions. The new method only requires nanollter samples, is easy to implement, and also provides diffusivities of the free analyte and the formed complex. The technique is based on signal analysis of temporal variances obtained for pressure driven flows in micrometer sized fused silica capillaries.

Originalsprog	Engelsk
Tidsskrift	Journal of the American Chemical Society
Vol/bind	132
Udgave nummer	12
Sider (fra-til)	4070-4071
ISSN	0002-7863
DOI	https://doi.org/10.1021/ja100484d
Status	Udgivet - 31 mar. 2010

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title = "Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples",

abstract = "Chemical Figure Presented Flow Induced Dispersion Analysis (FIDA) is presented as a new approach to characterize noncovalent Interactions. The new method only requires nanollter samples, is easy to implement, and also provides diffusivities of the free analyte and the formed complex. The technique is based on signal analysis of temporal variances obtained for pressure driven flows in micrometer sized fused silica capillaries.",

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AU - Østergaard, Jesper

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N2 - Chemical Figure Presented Flow Induced Dispersion Analysis (FIDA) is presented as a new approach to characterize noncovalent Interactions. The new method only requires nanollter samples, is easy to implement, and also provides diffusivities of the free analyte and the formed complex. The technique is based on signal analysis of temporal variances obtained for pressure driven flows in micrometer sized fused silica capillaries.

AB - Chemical Figure Presented Flow Induced Dispersion Analysis (FIDA) is presented as a new approach to characterize noncovalent Interactions. The new method only requires nanollter samples, is easy to implement, and also provides diffusivities of the free analyte and the formed complex. The technique is based on signal analysis of temporal variances obtained for pressure driven flows in micrometer sized fused silica capillaries.

KW - Former Faculty of Pharmaceutical Sciences

U2 - 10.1021/ja100484d

DO - 10.1021/ja100484d

M3 - Journal article

C2 - 20201527

SN - 0002-7863

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EP - 4071

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 12

ER -

Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples

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