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Feasibility of Exposure-Response Analyses for Clinical Dose-Ranging Studies of Drug Combinations
Theodoros Papathanasiou, Anders Strathe, Andrew C Hooker,
Trine Meldgaard Lund
, Rune Viig Overgaard
Department of Drug Design and Pharmacology
2
Citations (Scopus)
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Dive into the research topics of 'Feasibility of Exposure-Response Analyses for Clinical Dose-Ranging Studies of Drug Combinations'. Together they form a unique fingerprint.
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Keyphrases
Exposure Analysis
100%
Dose-ranging Study
100%
Exposure-response
100%
Drug Combination
100%
Pharmacodynamic Interactions
60%
Interaction Model
40%
Previous Knowledge
40%
Response Profiles
40%
Parameter Estimation
40%
Mono-component
40%
Combined Exposure
20%
Simulation Study
20%
General Trends
20%
Dose Selection
20%
Optimal Dose
20%
Interaction Parameter
20%
Drug Interactions
20%
Drug Effects
20%
Pharmacodynamics
20%
Clinical Endpoints
20%
Design Phase
20%
Phase II Trial
20%
Dose Combination
20%
Trial Size
20%
Appropriate Dose
20%
Pharmacology, Toxicology and Pharmaceutical Science
Combination Drug
100%
Pharmacodynamics
100%
Phase II Trials
33%
Pharmacodynamic Parameter
33%