Expanding the Optical Trapping Range of Lipid Vesicles to the Nanoscale

Pól Martin Bendix, Lene Broeng Oddershede

39 Citations (Scopus)

Abstract

Small unilamellar lipid vesicles with diameters down to 50 nm enclosing high refractive index sucrose cores can be optically trapped individually in three dimensions using a focused laser beam. Combined optical trapping and confocal microscopy allows for simultaneous quantitative measurements of the forces exerted on individual vesicles and of their size and shape. The position of individual vesicles in three dimensions is measured with nanometer spatial and ∼10 μs temporal resolution.

Original languageEnglish
JournalNano Letters
Volume11
Issue number12
Pages (from-to)5431-5437
ISSN1530-6984
DOIs
Publication statusPublished - 14 Dec 2011

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