Expanding the Optical Trapping Range of Lipid Vesicles to the Nanoscale

TY - JOUR

T1 - Expanding the Optical Trapping Range of Lipid Vesicles to the Nanoscale

AU - Bendix, Pól Martin

AU - Oddershede, Lene Broeng

PY - 2011/12/14

Y1 - 2011/12/14

N2 - Small unilamellar lipid vesicles with diameters down to 50 nm enclosing high refractive index sucrose cores can be optically trapped individually in three dimensions using a focused laser beam. Combined optical trapping and confocal microscopy allows for simultaneous quantitative measurements of the forces exerted on individual vesicles and of their size and shape. The position of individual vesicles in three dimensions is measured with nanometer spatial and ∼10 μs temporal resolution.

AB - Small unilamellar lipid vesicles with diameters down to 50 nm enclosing high refractive index sucrose cores can be optically trapped individually in three dimensions using a focused laser beam. Combined optical trapping and confocal microscopy allows for simultaneous quantitative measurements of the forces exerted on individual vesicles and of their size and shape. The position of individual vesicles in three dimensions is measured with nanometer spatial and ∼10 μs temporal resolution.

U2 - 10.1021/nl203200g

DO - 10.1021/nl203200g

M3 - Journal article

SN - 1530-6984

VL - 11

SP - 5431

EP - 5437

JO - Nano Letters

JF - Nano Letters

IS - 12

ER -