Abstract
Topical negative pressure, commonly used in wound therapy, has been shown to increase blood flow and stimulate angiogenesis in subcutaneous tissue and skeletal muscle. In wound therapy, intermittent negative pressure is often preferred to continuous negative pressure as tissue exposed to intermittent therapy shows twice as much granulation tissue formation than that exposed to continuous pressure after 2 weeks of therapy. The present study was designed to elucidate the differences in microvascular blood flow in the left anterior descending artery area between continuous and intermittent myocardial topical negative pressure of -50 mmHg.
| Original language | English |
|---|---|
| Journal | Journal of Cardiovascular Medicine (Hagerstown) |
| Volume | 9 |
| Issue number | 8 |
| Pages (from-to) | 813-9 |
| Number of pages | 7 |
| ISSN | 1558-2027 |
| DOIs | |
| Publication status | Published - Aug 2008 |
Keywords
- Animals
- Collateral Circulation
- Coronary Circulation
- Coronary Vessels
- Disease Models, Animal
- Female
- Laser-Doppler Flowmetry
- Male
- Microcirculation
- Myocardial Reperfusion Injury
- Negative-Pressure Wound Therapy
- Swine
- Treatment Outcome