Evaluation of continuous and intermittent myocardial topical negative pressure

Sandra Lindstedt; Malin Malmsjö; Bodil Gesslein; Richard Ingemansson

doi:10.2459/JCM.0b013e3282f85bda

Evaluation of continuous and intermittent myocardial topical negative pressure

Sandra Lindstedt, Malin Malmsjö, Bodil Gesslein, Richard Ingemansson

Neuronal Signalling

9 Citationer (Scopus)

Abstract

Topical negative pressure, commonly used in wound therapy, has been shown to increase blood flow and stimulate angiogenesis in subcutaneous tissue and skeletal muscle. In wound therapy, intermittent negative pressure is often preferred to continuous negative pressure as tissue exposed to intermittent therapy shows twice as much granulation tissue formation than that exposed to continuous pressure after 2 weeks of therapy. The present study was designed to elucidate the differences in microvascular blood flow in the left anterior descending artery area between continuous and intermittent myocardial topical negative pressure of -50 mmHg.

Originalsprog	Engelsk
Tidsskrift	Journal of Cardiovascular Medicine (Hagerstown)
Vol/bind	9
Udgave nummer	8
Sider (fra-til)	813-9
Antal sider	7
ISSN	1558-2027
DOI	https://doi.org/10.2459/JCM.0b013e3282f85bda
Status	Udgivet - aug. 2008

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10.2459/JCM.0b013e3282f85bda

Citationsformater

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title = "Evaluation of continuous and intermittent myocardial topical negative pressure",

abstract = "Topical negative pressure, commonly used in wound therapy, has been shown to increase blood flow and stimulate angiogenesis in subcutaneous tissue and skeletal muscle. In wound therapy, intermittent negative pressure is often preferred to continuous negative pressure as tissue exposed to intermittent therapy shows twice as much granulation tissue formation than that exposed to continuous pressure after 2 weeks of therapy. The present study was designed to elucidate the differences in microvascular blood flow in the left anterior descending artery area between continuous and intermittent myocardial topical negative pressure of -50 mmHg.",

keywords = "Animals, Collateral Circulation, Coronary Circulation, Coronary Vessels, Disease Models, Animal, Female, Laser-Doppler Flowmetry, Male, Microcirculation, Myocardial Reperfusion Injury, Negative-Pressure Wound Therapy, Swine, Treatment Outcome",

author = "Sandra Lindstedt and Malin Malmsj{\"o} and Bodil Gesslein and Richard Ingemansson",

year = "2008",

month = aug,

doi = "10.2459/JCM.0b013e3282f85bda",

language = "English",

volume = "9",

pages = "813--9",

journal = "Journal of Cardiovascular Medicine",

issn = "1558-2027",

publisher = "Lippincott Williams & Wilkins",

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TY - JOUR

T1 - Evaluation of continuous and intermittent myocardial topical negative pressure

AU - Lindstedt, Sandra

AU - Malmsjö, Malin

AU - Gesslein, Bodil

AU - Ingemansson, Richard

PY - 2008/8

Y1 - 2008/8

N2 - Topical negative pressure, commonly used in wound therapy, has been shown to increase blood flow and stimulate angiogenesis in subcutaneous tissue and skeletal muscle. In wound therapy, intermittent negative pressure is often preferred to continuous negative pressure as tissue exposed to intermittent therapy shows twice as much granulation tissue formation than that exposed to continuous pressure after 2 weeks of therapy. The present study was designed to elucidate the differences in microvascular blood flow in the left anterior descending artery area between continuous and intermittent myocardial topical negative pressure of -50 mmHg.

AB - Topical negative pressure, commonly used in wound therapy, has been shown to increase blood flow and stimulate angiogenesis in subcutaneous tissue and skeletal muscle. In wound therapy, intermittent negative pressure is often preferred to continuous negative pressure as tissue exposed to intermittent therapy shows twice as much granulation tissue formation than that exposed to continuous pressure after 2 weeks of therapy. The present study was designed to elucidate the differences in microvascular blood flow in the left anterior descending artery area between continuous and intermittent myocardial topical negative pressure of -50 mmHg.

KW - Animals

KW - Collateral Circulation

KW - Coronary Circulation

KW - Coronary Vessels

KW - Disease Models, Animal

KW - Female

KW - Laser-Doppler Flowmetry

KW - Male

KW - Microcirculation

KW - Myocardial Reperfusion Injury

KW - Negative-Pressure Wound Therapy

KW - Swine

KW - Treatment Outcome

U2 - 10.2459/JCM.0b013e3282f85bda

DO - 10.2459/JCM.0b013e3282f85bda

M3 - Journal article

C2 - 18607247

SN - 1558-2027

VL - 9

SP - 813

EP - 819

JO - Journal of Cardiovascular Medicine

JF - Journal of Cardiovascular Medicine

IS - 8

ER -

Evaluation of continuous and intermittent myocardial topical negative pressure

Abstract

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