Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Eileen D. Kuempel; Marie-Claude Jaurand; Peter Møller; Yasuo Morimoto; Norihiro Kobayashi; Kent E. Pinkerton; Linda M. Sargent; Roel C. H. Vermeulen; Bice Fubini; Agnes B. Kane

doi:10.1080/10408444.2016.1206061

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Eileen D. Kuempel, Marie-Claude Jaurand, Peter Møller, Yasuo Morimoto, Norihiro Kobayashi, Kent E. Pinkerton, Linda M. Sargent, Roel C. H. Vermeulen, Bice Fubini, Agnes B. Kane

Section of Environmental Health

52 Citations (Scopus)

Original language	English
Journal	Critical Reviews in Toxicology
Volume	47
Issue number	1
Pages (from-to)	1-58
Number of pages	58
ISSN	1040-8444
DOIs	https://doi.org/10.1080/10408444.2016.1206061
Publication status	Published - 2 Jan 2017

Keywords

Cancer mechanisms
carbon nanofibers
carbon nanotubes
cell proliferation
fibrosis
genotoxicity
inflammation
lung cancer
mesothelioma
particle retention
pulmonary
translocation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Kuempel, E. D., Jaurand, M.-C., Møller, P., Morimoto, Y., Kobayashi, N., Pinkerton, K. E., Sargent, L. M., Vermeulen, R. C. H., Fubini, B., & Kane, A. B. (2017). Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans. Critical Reviews in Toxicology, 47(1), 1-58. https://doi.org/10.1080/10408444.2016.1206061

Kuempel, ED, Jaurand, M-C, Møller, P, Morimoto, Y, Kobayashi, N, Pinkerton, KE, Sargent, LM, Vermeulen, RCH, Fubini, B & Kane, AB 2017, 'Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans', Critical Reviews in Toxicology, vol. 47, no. 1, pp. 1-58. https://doi.org/10.1080/10408444.2016.1206061

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AU - Møller, Peter

AU - Morimoto, Yasuo

AU - Kobayashi, Norihiro

AU - Pinkerton, Kent E.

AU - Sargent, Linda M.

AU - Vermeulen, Roel C. H.

AU - Fubini, Bice

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KW - carbon nanofibers

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KW - fibrosis

KW - genotoxicity

KW - inflammation

KW - lung cancer

KW - mesothelioma

KW - particle retention

KW - pulmonary

KW - translocation

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Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Keywords

UN SDGs

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