Ethical principles for the use of human cellular biotechnologies

Paul Root Wolpe; Karen S. Rommelfanger; Jason  Borenstein; Cory Andrew  Labrecque; Jeffrey L.  Bennetzen; Sarah Boyd; Patrick  Gaudray; Sara Giordano; Ock-Joo  Kim; Magnin  Thierry; Robert M.  Nerem; Joel Michael  Reynolds; Nils-Eric  Sahlin; David Brandin  Weir; Judy Awong-Taylor; Mickey Gjerris; Celeste M.  Condit; Marcy  Darnovsky; Margaret  Offermann; Arri Eisen; Edward Queen; Lars  Ahrlund-Richter; Kasey Karen; Todd Kuiken; William  Sexson; Elizabeth  Sudduth; Wendell  Wallach; Christopher  Warner; Mark Yarborough; Kevin York-Simmons; Jonathan K.  Crane; Yi Deng; Peng Jin; Benjamin  Capps; Fazal Khan; Robert  Kirkman; Jeanne  Loring; Heather Ross; Stephanie  Pollitt; Kathy  Kinlaw; Aaron  Levine; Neal Dickert; Chad Gaffield; Chris Gunter; Elisabeth  Javazon; Steven  Kraftchick; Justin  Lowenthal; Ubaka  Ogbogu; Laura  Szymanski; Elaine  Walker; Kelly Shaw; Joachim  Boldt; Estella Chen; Mark Douglas; Karol  Estrada; Kelly E. Happe; MyungSun Lee; Jeantine E.  Lunshof; Seon Yeo Min; Rebecca D.  Pentz; Ilina  Singh; Jordan  Yeager; Boris  Yudin

doi:10.1038/nbt.4007

Ethical principles for the use of human cellular biotechnologies

Paul Root Wolpe^*, Karen S. Rommelfanger, Jason Borenstein, Cory Andrew Labrecque, Jeffrey L. Bennetzen, Sarah Boyd, Patrick Gaudray, Sara Giordano, Ock-Joo Kim, Magnin Thierry, Robert M. Nerem, Joel Michael Reynolds, Nils-Eric Sahlin, David Brandin Weir, Judy Awong-Taylor, Mickey Gjerris, Celeste M. Condit, Marcy Darnovsky, Margaret Offermann, Arri EisenEdward Queen, Lars Ahrlund-Richter, Kasey Karen, Todd Kuiken, William Sexson, Elizabeth Sudduth, Wendell Wallach, Christopher Warner, Mark Yarborough, Kevin York-Simmons, Jonathan K. Crane, Yi Deng, Peng Jin, Benjamin Capps, Fazal Khan, Robert Kirkman, Jeanne Loring, Heather Ross, Stephanie Pollitt, Kathy Kinlaw, Aaron Levine, Neal Dickert, Chad Gaffield, Chris Gunter, Elisabeth Javazon, Steven Kraftchick, Justin Lowenthal, Ubaka Ogbogu, Laura Szymanski, Elaine Walker, Kelly Shaw, Joachim Boldt, Estella Chen, Mark Douglas, Karol Estrada, Kelly E. Happe, MyungSun Lee, Jeantine E. Lunshof, Seon Yeo Min, Rebecca D. Pentz, Ilina Singh, Jordan Yeager, Boris Yudin

^*Corresponding author for this work

Section for Consumption, Bioethics and Governance

6 Citations (Scopus)

Abstract

Recent developments in bioengineering promise the possibility of new diagnostic and treatment strategies, novel industrial processes, and innovative approaches to thorny problems in fields such as nutrition, agriculture, and biomanufacturing. As modern genetics has matured and developed technologies of increasing power, debates overrisk assessments and proper applications of the technology, and over who should have decision-making power over such issues, have become more prominent. Recently, some scientists have advocated that ethicists step out of the way, whereas others have called for greater ethical scrutiny, or even for moratoria on some lines of research1,2. As a community, however, we must together determine the proper application of these powerful biological tools. This paper, a consensus statement of a group of interdisciplinary delegates drawn from the top biotech-producing countries of the world, offers a set of ethical principles to contribute to the ethical conversation about human cellular biotechnological research moving forward.

Original language	English
Journal	Nature Biotechnology
Volume	35
Issue number	11
Pages (from-to)	1050-1058
Number of pages	9
ISSN	1087-0156
DOIs	https://doi.org/10.1038/nbt.4007
Publication status	Published - 2017

Access to Document

10.1038/nbt.4007

Cite this

Wolpe, P. R., Rommelfanger, K. S., Borenstein, J., Labrecque, C. A., Bennetzen, J. L., Boyd, S., Gaudray, P., Giordano, S., Kim, O-J., Thierry, M., Nerem, R. M., Reynolds, J. M., Sahlin, N-E., Weir, D. B., Awong-Taylor, J., Gjerris, M., Condit, C. M., Darnovsky, M., Offermann, M., ... Yudin, B. (2017). Ethical principles for the use of human cellular biotechnologies. Nature Biotechnology, 35(11), 1050-1058. https://doi.org/10.1038/nbt.4007

Wolpe, PR, Rommelfanger, KS, Borenstein, J, Labrecque, CA, Bennetzen, JL, Boyd, S, Gaudray, P, Giordano, S, Kim, O-J, Thierry, M, Nerem, RM, Reynolds, JM, Sahlin, N-E, Weir, DB, Awong-Taylor, J, Gjerris, M, Condit, CM, Darnovsky, M, Offermann, M, Eisen, A, Queen, E, Ahrlund-Richter, L, Karen, K, Kuiken, T, Sexson, W, Sudduth, E, Wallach, W, Warner, C, Yarborough, M, York-Simmons, K, Crane, JK, Deng, Y, Jin, P, Capps, B, Khan, F, Kirkman, R, Loring, J, Ross, H, Pollitt, S, Kinlaw, K, Levine, A, Dickert, N, Gaffield, C, Gunter, C, Javazon, E, Kraftchick, S, Lowenthal, J, Ogbogu, U, Szymanski, L, Walker, E, Shaw, K, Boldt, J, Chen, E, Douglas, M, Estrada, K, Happe, KE, Lee, M, Lunshof, JE, Min, SY, Pentz, RD, Singh, I, Yeager, J & Yudin, B 2017, 'Ethical principles for the use of human cellular biotechnologies', Nature Biotechnology, vol. 35, no. 11, pp. 1050-1058. https://doi.org/10.1038/nbt.4007

@article{bc5abe45369b409ca8c5a4b83cba4e93,

title = "Ethical principles for the use of human cellular biotechnologies",

abstract = "Recent developments in bioengineering promise the possibility of new diagnostic and treatment strategies, novel industrial processes, and innovative approaches to thorny problems in fields such as nutrition, agriculture, and biomanufacturing. As modern genetics has matured and developed technologies of increasing power, debates overrisk assessments and proper applications of the technology, and over who should have decision-making power over such issues, have become more prominent. Recently, some scientists have advocated that ethicists step out of the way, whereas others have called for greater ethical scrutiny, or even for moratoria on some lines of research1,2. As a community, however, we must together determine the proper application of these powerful biological tools. This paper, a consensus statement of a group of interdisciplinary delegates drawn from the top biotech-producing countries of the world, offers a set of ethical principles to contribute to the ethical conversation about human cellular biotechnological research moving forward.",

author = "Wolpe, {Paul Root} and Rommelfanger, {Karen S.} and Jason Borenstein and Labrecque, {Cory Andrew} and Bennetzen, {Jeffrey L.} and Sarah Boyd and Patrick Gaudray and Sara Giordano and Ock-Joo Kim and Magnin Thierry and Nerem, {Robert M.} and Reynolds, {Joel Michael} and Nils-Eric Sahlin and Weir, {David Brandin} and Judy Awong-Taylor and Mickey Gjerris and Condit, {Celeste M.} and Marcy Darnovsky and Margaret Offermann and Arri Eisen and Edward Queen and Lars Ahrlund-Richter and Kasey Karen and Todd Kuiken and William Sexson and Elizabeth Sudduth and Wendell Wallach and Christopher Warner and Mark Yarborough and Kevin York-Simmons and Crane, {Jonathan K.} and Yi Deng and Peng Jin and Benjamin Capps and Fazal Khan and Robert Kirkman and Jeanne Loring and Heather Ross and Stephanie Pollitt and Kathy Kinlaw and Aaron Levine and Neal Dickert and Chad Gaffield and Chris Gunter and Elisabeth Javazon and Steven Kraftchick and Justin Lowenthal and Ubaka Ogbogu and Laura Szymanski and Elaine Walker and Kelly Shaw and Joachim Boldt and Estella Chen and Mark Douglas and Karol Estrada and Happe, {Kelly E.} and MyungSun Lee and Lunshof, {Jeantine E.} and Min, {Seon Yeo} and Pentz, {Rebecca D.} and Ilina Singh and Jordan Yeager and Boris Yudin",

year = "2017",

doi = "10.1038/nbt.4007",

language = "English",

volume = "35",

pages = "1050--1058",

journal = "Nature Biotechnology",

issn = "1087-0156",

publisher = "nature publishing group",

number = "11",

}

TY - JOUR

T1 - Ethical principles for the use of human cellular biotechnologies

AU - Wolpe, Paul Root

AU - Rommelfanger, Karen S.

AU - Borenstein, Jason

AU - Labrecque, Cory Andrew

AU - Bennetzen, Jeffrey L.

AU - Boyd, Sarah

AU - Gaudray, Patrick

AU - Giordano, Sara

AU - Kim, Ock-Joo

AU - Thierry, Magnin

AU - Nerem, Robert M.

AU - Reynolds, Joel Michael

AU - Sahlin, Nils-Eric

AU - Weir, David Brandin

AU - Awong-Taylor, Judy

AU - Gjerris, Mickey

AU - Condit, Celeste M.

AU - Darnovsky, Marcy

AU - Offermann, Margaret

AU - Eisen, Arri

AU - Queen, Edward

AU - Ahrlund-Richter, Lars

AU - Karen, Kasey

AU - Kuiken, Todd

AU - Sexson, William

AU - Sudduth, Elizabeth

AU - Wallach, Wendell

AU - Warner, Christopher

AU - Yarborough, Mark

AU - York-Simmons, Kevin

AU - Crane, Jonathan K.

AU - Deng, Yi

AU - Jin, Peng

AU - Capps, Benjamin

AU - Khan, Fazal

AU - Kirkman, Robert

AU - Loring, Jeanne

AU - Ross, Heather

AU - Pollitt, Stephanie

AU - Kinlaw, Kathy

AU - Levine, Aaron

AU - Dickert, Neal

AU - Gaffield, Chad

AU - Gunter, Chris

AU - Javazon, Elisabeth

AU - Kraftchick, Steven

AU - Lowenthal, Justin

AU - Ogbogu, Ubaka

AU - Szymanski, Laura

AU - Walker, Elaine

AU - Shaw, Kelly

AU - Boldt, Joachim

AU - Chen, Estella

AU - Douglas, Mark

AU - Estrada, Karol

AU - Happe, Kelly E.

AU - Lee, MyungSun

AU - Lunshof, Jeantine E.

AU - Min, Seon Yeo

AU - Pentz, Rebecca D.

AU - Singh, Ilina

AU - Yeager, Jordan

AU - Yudin, Boris

PY - 2017

Y1 - 2017

N2 - Recent developments in bioengineering promise the possibility of new diagnostic and treatment strategies, novel industrial processes, and innovative approaches to thorny problems in fields such as nutrition, agriculture, and biomanufacturing. As modern genetics has matured and developed technologies of increasing power, debates overrisk assessments and proper applications of the technology, and over who should have decision-making power over such issues, have become more prominent. Recently, some scientists have advocated that ethicists step out of the way, whereas others have called for greater ethical scrutiny, or even for moratoria on some lines of research1,2. As a community, however, we must together determine the proper application of these powerful biological tools. This paper, a consensus statement of a group of interdisciplinary delegates drawn from the top biotech-producing countries of the world, offers a set of ethical principles to contribute to the ethical conversation about human cellular biotechnological research moving forward.

AB - Recent developments in bioengineering promise the possibility of new diagnostic and treatment strategies, novel industrial processes, and innovative approaches to thorny problems in fields such as nutrition, agriculture, and biomanufacturing. As modern genetics has matured and developed technologies of increasing power, debates overrisk assessments and proper applications of the technology, and over who should have decision-making power over such issues, have become more prominent. Recently, some scientists have advocated that ethicists step out of the way, whereas others have called for greater ethical scrutiny, or even for moratoria on some lines of research1,2. As a community, however, we must together determine the proper application of these powerful biological tools. This paper, a consensus statement of a group of interdisciplinary delegates drawn from the top biotech-producing countries of the world, offers a set of ethical principles to contribute to the ethical conversation about human cellular biotechnological research moving forward.

U2 - 10.1038/nbt.4007

DO - 10.1038/nbt.4007

M3 - Journal article

C2 - 29121024

AN - SCOPUS:85033599547

SN - 1087-0156

VL - 35

SP - 1050

EP - 1058

JO - Nature Biotechnology

JF - Nature Biotechnology

IS - 11

ER -

Ethical principles for the use of human cellular biotechnologies

Abstract

Access to Document

Fingerprint

Cite this