Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

Philip J. Sassene, Mette D. Mosgaard, Korbinian Löbmann, Huiling Mu, Flemming Hofmann Larsen, Thomas Rades, Anette Müllertz

25 Citations (Scopus)
Original languageEnglish
JournalMolecular Pharmaceutics
Volume12
Issue number11
Pages (from-to)4067-4076
Number of pages10
ISSN1543-8384
DOIs
Publication statusPublished - 22 Sept 2015

Keywords

  • lipid-based drug delivery systems
  • self-nanoemuslifying drug delivery systems
  • nuclear magnetic resonance spectroscopy
  • differential scanning calorimetry
  • solid-state characterization
  • amorphous
  • weak bases
  • interactions

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